N-Acetyl-D-glutamic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 19146-55-5 |
| Product name | N-Acetyl-D-glutamic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Acetyl-D-glutamic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Acetyl-D-glutamic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Acetyl-D-glutamic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Targeted therapy for urea cycle disorders (e.g., N-acetylglutamate synthase deficiency), supplementing endogenous N-acetyl-D-glutamate to activate carbamoyl phosphate synthetase I (CPSI) | Administered intravenously as an enzyme activator in the mitochondrial urea cycle initiation step |
| Pharmaceuticals | Adjunct component in combined L-arginine and L-citrulline therapy to improve nitrogen clearance efficiency in patients with hyperammonemia | Used in combination with arginine hydrochloride to enhance CPSI activity and increase the conversion rate of ammonia to urea |
| Biological Reagents | Research tool for modulating nitrogen metabolism pathways in cell culture, used to model or correct urea cycle dysfunction | Added to serum-free or chemically defined media (e.g.,GMEM) at typical concentrations of 0.1–1.0 mM |
| Diagnostics | Reference standard or calibrator in in vitro diagnostic kits for urea cycle disorders | Quantitative reference material for HPLC-MS/MS or enzymatic colorimetric assay methods |
Manufacturing Quality Control of N-Acetyl-D-glutamic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration with NaOH | Quantifies N-acetyl-D-glutamic acid by neutralization of carboxylic acid groups using standardized sodium hydroxide solution. |
| Related Substances | HPLC with UV Detection | Separates and quantifies impurities and degradation products based on retention time and UV absorbance at 200-220 nm. |
| Optical Rotation | [a]D Measurement | Determines specific optical rotation using a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry | Measures weight loss after drying at 105 C under vacuum to determine volatile content including residual solvents and moisture. |
| Residual Solvents | Gas Chromatography (GC-FID) | Quantifies common organic solvents (e.g., methanol, acetone, ethyl acetate) by separation and flame ionization detection. |
| Heavy Metals | ICP-OES | Simultaneously determines trace metal contaminants (e.g., Pb, Cd, As, Hg, Ni) via atomic emission spectroscopy after acid digestion. |
| Chloride Content | Potentiometric Titration with AgNO3 | Measures chloride ions by titration with silver nitrate using a silver indicator electrode. |
| Sulfated Ash | Gravimetric Ash Residue Analysis | Determines inorganic residue after incineration with sulfuric acid followed by high-temperature ashing. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a 1% w/v aqueous solution using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using angular scattering intensity of laser light. |
| Microbial Limits | Membrane Filtration and Colony Counting | Detects aerobic microorganisms and specified pathogens by filtration, culture on selective media, and enumeration. |
| Water Content | Karl Fischer Coulometric Titration | Quantifies total water content via electrochemical generation of iodine and stoichiometric reaction with water. |
Technical Specifications of N-Acetyl-D-glutamic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 192°C - 196°C |
| Optical Rotation | -12.0° to -14.0° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Acetyl-D-glutamic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Acetyl-D-glutamic acid
Packaging of N-Acetyl-D-glutamic acid
Industrial N-Acetyl-D-glutamic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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