China Factory Direct
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| CAS number | 1918-77-0 |
| Product name | 2-Thiopheneacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic drug intermediate for preparing active pharmaceutical ingredients (APIs), including anti-inflammatory and antiviral agents | Acetyl group introduced via functionalization of the thiophene ring, followed by coupling or substitution reactions to construct the target molecular structure |
| Agricultural Chemicals | Used to synthesize novel agrochemical intermediates, such as fungicides and insecticides | 2-Thiopheneacetic acid serves as the starting material; functionalized compounds are prepared via esterification, amidation, or halogenation |
| Polymers & Materials | Employed as a functional monomer or crosslinking agent for polymer modification | Carboxyl group participates in condensation polymerization with polyester or polyamide systems to enhance thermal stability and chemical resistance |
| Fine Chemicals | Used to prepare fluorescent dyes, catalyst ligands, and organic synthesis reagents | Leverages dual reactivity of the carboxyl group and thiophene ring for metal coordination or coupling reactions (e.g., Suzuki coupling) |
| Life Sciences Research | Serves as a synthetic precursor for bioactive molecular probes or labeling agents | Chemically modified to conjugate 2-thiopheneacetic acid to biomacromolecules (e.g., proteins, nucleic acids) for detection and analysis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 230-254 nm, comparing peak area to a certified reference standard. |
| Appearance | Visual Inspection | Assessment of physical state and color against a white background under controlled lighting; acceptable as white to off-white crystalline solid. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric (Oven Drying) | Mass loss measured after drying sample at 105 C for 2 hours; reflects volatile impurities and residual solvents. |
| Residue on Ignition | Gravimetric (Sulfated Ash) | Mass of inorganic residue remaining after high-temperature incineration (600-800 C) of the sample. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma excitation. |
| Related Substances | HPLC-DAD | Identification and quantification of structurally related impurities using HPLC with diode-array detection and reference standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water content via iodine-sulfur dioxide reaction in pyridine/methanol medium. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of pH in a 1% w/v aqueous suspension using calibrated glass electrode and pH meter. |
| Solvent Residues (e.g., Ethanol, Acetone) | GC-FID | Quantification of residual organic solvents by gas chromatography with flame ionization detection using internal standard calibration. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passed through a solution in a standardized cell at specified concentration and wavelength (589 nm). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-brown solid |
| Purity | >=98.5% (LC-MS) |
| Melting Point | 76–79 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.