China Factory Direct
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| CAS number | 192130-34-0 |
| Product name | 4-(2-AMINO-ETHYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key Intermediate | Used in the synthesis of macrolide antibiotics (e.g., tylosin, tilmicosin) and their derivatives, where the amine group forms a covalent bond with the drug core to construct the active pharmaceutical ingredient. |
| Pharmaceutical Chemicals | Drug Discovery Building Block | Serves as a bifunctional linker containing both a piperidine ring and an ethylenediamine chain, enabling the construction of candidate drug molecules with tailored pharmacokinetic properties. |
| Biochemistry | Bioconjugation Reagent | Reacts via its primary amine group (–NH₂) with carboxyl groups or activated esters on biomolecules (e.g., proteins, peptides) to form stable amide bonds for labeling or modification. |
| Research Chemicals | Organic Synthesis Reagent | Applied in combinatorial library synthesis and drug screening to introduce nitrogen-containing heterocyclic scaffolds into target molecules. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities via retention time comparison and peak area integration. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, EtOAc) by gas chromatographic separation and flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by stoichiometric reaction of iodine with water in a methanol-based reagent. |
| Residual Metals (e.g., Pd, Ni, Fe) | ICP-MS | Quantifies trace metal catalysts and contaminants using plasma ionization and mass spectrometric detection. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions based on anion exchange chromatography with conductivity detection. |
| Optical Rotation | [a]D Measurement | Measures specific rotation of chiral compound in solution using polarized light to confirm stereochemical integrity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled lighting conditions. |
| pH (1% w/v aqueous solution) | pH Meter | Measures hydrogen ion activity in aqueous suspension to detect acidic/basic degradation products. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by weight loss after drying under specified temperature and vacuum conditions. |
| Residual BOC Protecting Group | HPLC-UV or NMR | Quantifies unreacted or cleaved BOC group by comparing characteristic peak areas (HPLC) or tert-butyl signal integration (NMR). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
| Optical Rotation | +15.0 to +19.0° (c=1, CHCl3) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.