China Factory Direct
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| CAS number | 19237-84-4 |
| Product name | Prazosin hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Active pharmaceutical ingredient (API) for antihypertensive drugs | Used as a selective α1-adrenergic receptor blocker in the manufacture of drug formulations for mild-to-moderate hypertension, lowering blood pressure via vasodilation of vascular smooth muscle. |
| Pharmaceutical Industry | Drug for benign prostatic hyperplasia (BPH) treatment | Applied to relax smooth muscle in the prostate and bladder neck—leveraging its α1-receptor blockade—to improve urinary obstruction symptoms; incorporated into related therapeutic formulations. |
| Pharmaceutical Industry | Adjunctive therapy for congestive heart failure | Employed as a vasodilator in combination therapy for refractory heart failure, reducing cardiac preload and afterload. |
| Research Sector | Pharmacological research tool compound | Serves as a reference α1-adrenergic receptor antagonist in receptor binding assays, studies of vascular smooth muscle contraction mechanisms, and drug screening models. |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectrophotometry (IR) | Perform infrared scanning of the sample and reference standard under the same conditions, comparing characteristic absorption peaks to confirm consistency of chemical structure. |
| High-Performance Liquid Chromatography (HPLC) | Verify consistency between sample and reference standard by comparing retention times; used as an auxiliary identification method. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase column (e.g., C18) and UV detector (around 254 nm) to determine the content of the active ingredient by external or internal standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate impurities using gradient or isocratic elution to detect degradation products or synthesis intermediates; calculate individual and total impurity limits. |
| Residual Solvents | Gas Chromatography (GC) | Determine residual levels of organic solvents (e.g., methanol, ethanol, acetone) used in manufacturing, in accordance with ICH guidelines. |
| Water Content | Karl Fischer Titration | Precisely measure water content in the sample by titration; suitable for quality control of active pharmaceutical ingredients (APIs). |
| Solution Clarity | Visual Turbidity Comparison | Dissolve the sample in a specified solvent and compare with a standard turbidity solution to assess whether the solution is clear. |
| Solution Color | Visual Color Comparison or Spectrophotometry | Compare with standard color solutions or measure absorbance at a specific wavelength to evaluate whether the solution color meets specifications. |
| Heavy Metals | Sulfide Colorimetry (Method I) or ICP-MS | After sample pretreatment, detect total levels of heavy metal elements such as lead, cadmium, and mercury using colorimetric or mass spectrometric methods. |
| Sulfated Ash (Residue on Ignition) | Residue on Ignition Test | Ignite the sample at high temperature until constant weight is achieved, then measure the amount of non-volatile inorganic residue. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRD) | Analyze characteristic peaks of drug crystal forms to ensure batch-to-batch consistency, especially important for controlling polymorphic drugs. |
| Particle Size Distribution | Laser Particle Size Analysis | Measure particle size and distribution of the active pharmaceutical ingredient, which influences dissolution rate and formulation performance. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 174–178°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.