11-a-Hydroxy canrenone methyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 192704-56-6 |
| Product name | 11-a-Hydroxy canrenone methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 11-a-Hydroxy canrenone methyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 11-a-Hydroxy canrenone methyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 11-a-Hydroxy canrenone methyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Eplerenone intermediate | Serves as a key intermediate; the methyl acrylate group is introduced via subsequent reactions to complete eplerenone synthesis. |
| Pharmaceutical Industry | Steroid drug synthesis | Used in structural modification and derivatization at the C11 hydroxyl and C17 side chain to produce other pharmacologically active steroid compounds. |
Manufacturing Quality Control of 11-a-Hydroxy canrenone methyl ester
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with UV detection (e.g., 240 nm), employing methanol-water or acetonitrile-water as the mobile phase for gradient or isocratic elution to quantitatively analyze the main component content. |
| Related Substances (Impurity) Testing | High-Performance Liquid Chromatography (HPLC) | Same as above; by adjusting the mobile phase and gradient program, separation between the main peak and impurity peaks is achieved to detect and quantify related substances (such as degradation products, isomers, etc.). |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace injection, capillary column (e.g., DB-624), and FID detector to detect organic solvents potentially remaining from production processes (e.g., methanol, ethanol, acetone, etc.). |
| Moisture Content | Karl Fischer Titration | Employs electrochemical principles to determine water content in samples, suitable for trace moisture analysis to ensure product stability. |
| Polymorph Analysis | X-Ray Powder Diffraction (XRD) | Analyzes the crystalline structure of solid samples to confirm the presence or absence of polymorphism, ensuring batch-to-batch consistency. |
| Melting Point | Melting Point Determination | Measures the melting temperature range using a melting point apparatus, serving as a physical constant for identification and purity assessment. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Prepares samples as potassium bromide pellets or uses an ATR accessory to obtain infrared absorption spectra, comparing them with reference spectra for structural confirmation. |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Utilizes chiral stationary phase columns to separate enantiomers, assessing optical purity to ensure correct stereochemistry. |
| Solution Clarity and Color | Visual Colorimetry / UV-Visible Spectrophotometry | Observes whether the dissolved sample solution is clear and free of abnormal color, or measures absorbance at specific wavelengths to control color quality. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Oven Drying Method | Heats the sample at a specified temperature and measures mass loss to assess volatile components or adsorbed water content. |
| Residue on Ignition | Sulfate Ashing Method | After high-temperature ignition, the residue weight is measured to detect inorganic impurities. |
Technical Specifications of 11-a-Hydroxy canrenone methyl ester
| Test Item | Specification |
|---|---|
| Appearance | Off-White To Pale Yellow Solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | +38.0 to +42.0 deg (c=1, in CHCl3) |
| Melting Point | 142.0 to 146.0 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 11-a-Hydroxy canrenone methyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 11-a-Hydroxy canrenone methyl ester
Safety Information of 11-a-Hydroxy canrenone methyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 11-a-Hydroxy canrenone methyl ester
Industrial 11-a-Hydroxy canrenone methyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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