2,5-DIFLUOROPHENYLBORONIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 193353-34-3 |
| Product name | 2,5-DIFLUOROPHENYLBORONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,5-DIFLUOROPHENYLBORONIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,5-DIFLUOROPHENYLBORONIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,5-DIFLUOROPHENYLBORONIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for anticancer drugs (e.g., ibrutinib) | Suzuki coupling reaction |
| Pharmaceuticals | Synthesis of small-molecule inhibitors | Aryl–aryl coupling |
| Chemicals | Building block for organic synthesis | Cross-coupling reaction |
| Materials Science | Synthesis of liquid crystal materials | Transition metal-catalyzed coupling |
Manufacturing Quality Control of 2,5-DIFLUOROPHENYLBORONIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and identification/quantification of impurities (e.g., residual starting materials, dehalogenated by-products, dimeric species) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., THF, toluene, methanol) against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification of trace metals after acid digestion, leveraging high sensitivity and isotopic resolution for compliance with ICH Q3D limits. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample water in anhydrous methanol-based medium. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Incineration at 700–800 °C followed by weighing of non-volatile inorganic residue, indicating inorganic impurities or catalyst residues. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid phase transition range; deviation from literature value (122–125 °C) indicates impurity presence or polymorphic variation. |
| Chloride Ion Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on anion-exchange column and quantitative detection of Cl⁻ via suppressed conductivity, per USP <231>. |
| Boron Content | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Quantification of total boron after microwave-assisted acid digestion, confirming stoichiometric equivalence to boronic acid functionality. |
| Optical Rotation | Polarimetry | Measurement of specific rotation ([α]D) to assess chiral purity; absence of optical activity confirms achirality (expected near 0° for this symmetric compound). |
Technical Specifications of 2,5-DIFLUOROPHENYLBORONIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 124-128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,5-DIFLUOROPHENYLBORONIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,5-DIFLUOROPHENYLBORONIC ACID
Safety Information of 2,5-DIFLUOROPHENYLBORONIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,5-DIFLUOROPHENYLBORONIC ACID
Industrial 2,5-DIFLUOROPHENYLBORONIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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