China Factory Direct
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| CAS number | 193629-39-9 |
| Product name | 1-BOC-3-BROMOMETHYLPIPERIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an intermediate in the synthesis of active pharmaceutical ingredients, including antipsychotics and antidepressants | Applied in nucleophilic substitution reactions at the bromine atom of N-BOC-3-(bromomethyl)piperidine to construct complex molecular frameworks |
| Organic Synthesis | Used to synthesize fine chemicals and functional molecules containing the piperidine moiety | Leveraged for SN2 substitution or coupling reactions (e.g., with amines or thiols) via its reactive bromomethyl group |
| Biomedical Research | Employed as a lead compound or probe molecule in targeted drug discovery | Modified through derivatization to incorporate fluorescent tags, biotin, or radioactive isotopes for biological assays |
| Polymer Materials | Used as a functional monomer in the synthesis of specialty polymers | Participates in free-radical polymerization or click chemistry reactions via its bromomethyl group to produce polymers with tailored functional groups |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, THF, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content by stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, etc.) after acid digestion, using isotopic detection for high sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion using plasma optical emission spectroscopy. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as solid-to-liquid phase change under controlled heating rate. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering pattern to derive volume-based particle size distribution. |
| Bulk Density | USP <616> Tap Density Test | Measurement of mass per unit volume before and after standardized mechanical tapping to assess powder flow and compaction behavior. |
| Microbial Limits | Membrane Filtration + TSA/SDA | Enumeration of aerobic bacteria, yeasts, and molds using membrane filtration followed by incubation on tryptic soy agar and sabouraud dextrose agar. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 72-76°C |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | [α]D²⁰ = -12° to -18° (c = 1 in CHCl₃) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.