(R)-1-Fmoc-3-pyrrolidinecarboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 193693-65-1 |
| Product name | (R)-1-Fmoc-3-pyrrolidinecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-1-Fmoc-3-pyrrolidinecarboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Peptide drug synthesis | Serves as a chiral building block (non-natural amino acid derivative) in solid-phase peptide synthesis (SPPS) using the Fmoc protection strategy to construct peptide sequences containing pyrrolidine motifs. |
| Pharmaceutical Chemicals | API intermediate synthesis | Used in the synthesis of active pharmaceutical ingredients (APIs), particularly as a structural building block for introducing pyrrolidine rings into protease inhibitors, antiviral agents, or cardiovascular drugs. |
| Scientific Research | New drug screening and development | Employed to construct stereochemically diverse compound libraries for screening lead compounds with specific biological activity. |
| Biochemistry | Biochemical reagent | Used as a specialized amino acid derivative in protein engineering or peptide chain modification to investigate structure–function relationships in proteins. |
Manufacturing Quality Control of (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 265 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., DMF, THF, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis after acid digestion; detection at sub-pptr levels using mass spectrometry. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of inorganic residue to assess inorganic ash content. |
| pH (1% w/v solution) | pH Potentiometry | Measurement using calibrated pH electrode in aqueous suspension to assess acidic/basic character from residual salts or degradation. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values per ISO 13320. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms via filtration, membrane transfer to agar media, and incubation per USP <61>. |
| Endotoxin Level | LAL Assay | Quantitative detection using Limulus Amebocyte Lysate reagent with chromogenic substrate, measuring absorbance change proportional to endotoxin concentration. |
Technical Specifications of (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148°C - 152°C |
| Optical Rotation | +22.0° to +26.0° (c=1, in DMF) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
Safety Information of (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-1-Fmoc-3-pyrrolidinecarboxylic acid
Industrial (R)-1-Fmoc-3-pyrrolidinecarboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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