Fmoc-L-beta-homoalanine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 193954-26-6 |
| Product name | Fmoc-L-beta-homoalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Fmoc-L-beta-homoalanine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-L-beta-homoalanine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-L-beta-homoalanine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a non-natural amino acid in peptide synthesis to construct peptide therapeutics with specific biological activity or enhanced stability | Employed as an Fmoc-protected β-homoproline derivative in solid-phase peptide synthesis (SPPS) for amide bond formation, followed by Fmoc deprotection using piperidine |
| Biochemical Research | Applied in studies of protein structure–function relationships, enzyme substrate specificity, and design of conformationally constrained peptides | Introduced into peptide chains to incorporate rigid or extended side-chain structures, thereby modulating secondary structure (e.g., β-turns or helices) |
| Medicinal Chemistry | Serves as a key intermediate in synthesizing β-amino acid-containing peptidomimetics to improve metabolic stability and membrane permeability | Coupled with standard α-amino acids or other non-natural amino acids in linear or cyclized peptide synthesis using the Fmoc/tBu strategy |
| Materials Science (Biomaterials) | Used to construct functional peptide materials with defined folding behavior or self-assembly properties | Leverages its rigid fluorenyl group and β-amino acid backbone to tune intermolecular interactions for nanostructure or hydrogel design |
Manufacturing Quality Control of Fmoc-L-beta-homoalanine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 260-280 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase with UV detection; L-isomer content calculated relative to total beta-homoalanine peak area. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in anhydrous methanol-based solvent. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection for quantification of common solvents (e.g., DMF, DCM, MeOH) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element detection of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 500-600 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Optical Rotation | [alpha]D Measurement | Specific rotation determined using sodium D-line light (589 nm) in solution, indicating chiral integrity and concentration. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed powder via light scattering pattern to determine D10, D50, D90 values. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Fmoc-deprotected species, dipeptides, oxidation products) using gradient HPLC. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a defined aqueous suspension (e.g., 1% w/v) using calibrated glass electrode. |
Technical Specifications of Fmoc-L-beta-homoalanine
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | +18° to +22° (c=1, in DMF) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Fmoc-L-beta-homoalanine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-L-beta-homoalanine
Packaging of Fmoc-L-beta-homoalanine
Industrial Fmoc-L-beta-homoalanine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply