(R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 194726-40-4 |
| Product name | (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used in the construction of chiral drug molecules as a precursor to (R)-piperidine derivatives; participates in coupling, hydrolysis, and deprotection reactions within multistep synthesis routes |
| Pharmaceutical R&D | Chiral building block | Introduces chiral centers in asymmetric synthesis for preparing biologically active piperidine compounds |
| Fine chemicals | Synthesis of specialty chemicals | Generates (R)-1-(tert-butoxycarbonyl)-3-piperidinecarboxylic acid via ester hydrolysis and Boc deprotection, followed by functional group modification and derivatization |
Manufacturing Quality Control of (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and enantiomeric excess calculation. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., EtOH, THF, DCM) against calibration standards. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent to determine trace water content via electrochemical reaction stoichiometry. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Ni, Fe) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residual Chloride | Ion Chromatography | Separation and conductivity detection of chloride ions in solution after sample dissolution and dilution. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to determine free carboxylic acid content. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to obtain volume-based particle size distribution (D10, D50, D90). |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., hydrolysis products, diastereomers) using gradient reverse-phase HPLC. |
| Residual Boc Group Content | 1H NMR Spectroscopy | Quantitative analysis of tert-butoxycarbonyl methyl protons relative to internal standard (e.g., 1,3,5-trimethoxybenzene) in deuterated chloroform. |
Technical Specifications of (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC) |
| Optical Rotation | -49.0 to -45.0 deg (c=1, in CHCl3) |
| Total Impurities | <=2.0% (GC) |
| Single Impurity | <=0.5% (GC) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER
Safety Information of (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER
Industrial (R)-1-BOC-3-HYDROXYMETHYLPIPERIDINE ETHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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