(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1948273-03-7 |
| Product name | (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1948273-03-7
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1948273-03-7 Supplier from China
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Industrial Applications of 1948273-03-7
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of specific pharmaceuticals | Used as an intermediate in defined synthetic steps |
| Biotechnology | Research and development of specific bioactive compounds | Prepared via biosynthetic or chemical synthesis processes |
| Fine Chemicals Manufacturing | Raw material or starting material | Prepared through multi-step synthesis |
Manufacturing Quality Control of 1948273-03-7
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at a characteristic wavelength, comparing peak area against a qualified reference standard. |
| Chiral Purity | (S,S,R)-Isomer Content | Chiral HPLC with polysaccharide-based column and UV detection; separation based on stereospecific interactions to resolve diastereomers and enantiomeric impurities. |
| Related Substances | HPLC-UV (Forced Degradation Compatible) | Separation and quantification of structurally related impurities (e.g., deamidated, oxidized, hydrolyzed forms) using gradient RP-HPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify Class 2/3 residual solvents (e.g., methanol, acetonitrile, DMF) per ICH Q3C. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample water. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Pd) using inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Direct titration using silver nitrate with silver-sulfide electrode detection of endpoint based on Ag⁺–Cl⁻ precipitation. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue post-hydrogenation using inductively coupled plasma optical emission spectrometry. |
| pH (1% w/v Aqueous Suspension) | pH Meter Measurement | Electrochemical measurement of hydrogen ion activity in aqueous suspension of the compound, calibrated per USP <791>. |
| Microbial Contamination | Membrane Filtration & Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
Technical Specifications of 1948273-03-7
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -138° to -132° (c=1, in 1M HCl) |
| Melting Point | 178°C to 182°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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| Lot/Batch Number | *Required fields | |
NMR Spectra of 1948273-03-7
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Industrial 1948273-03-7 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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