1-Chloroisoquinoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 19493-44-8 |
| Product name | 1-Chloroisoquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Chloroisoquinoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Chloroisoquinoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Chloroisoquinoline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antitumor, antiviral, or neuroactive compounds | Employed in constructing complex molecular scaffolds via nucleophilic substitution and coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Agrochemicals | Used in the synthesis of biologically active pesticides or plant growth regulators | Applied as a heterocyclic building block in multistep organic synthesis; chlorine atom introduced to modulate biological activity or metabolic stability |
| Fine Chemicals | Used as an organic synthesis intermediate for preparing fluorescent materials, ligands, or functionalized isoquinoline derivatives | Leverages reactivity of the chlorine atom for functional group transformations, including amination, cyanation, or metal-catalyzed cross-coupling |
Manufacturing Quality Control of 1-Chloroisoquinoline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or GC-MS | Quantitative determination by comparison of peak area against a certified reference standard using gas chromatography with flame ionization or mass spectrometric detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents based on retention time and peak area relative to internal/external standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration where iodine reacts stoichiometrically with water in a methanol-based reagent; endpoint detected amperometrically. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion by measuring atomic emission intensities at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using anion-exchange column and conductivity detection. |
| Related Substances | HPLC-UV | Separation of structurally similar impurities on a reversed-phase column with UV absorbance detection at 254 nm. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually as the temperature range over which solid transforms to liquid under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting conditions. |
| Acid Value | Acid-Base Titration | Neutralization of acidic impurities with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile inorganic residue remaining after high-temperature ashing of sample in a platinum crucible. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution of the compound in a defined cell pathlength and concentration. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after mechanical tapping of a known mass in a graduated cylinder. |
Technical Specifications of 1-Chloroisoquinoline
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Chloroisoquinoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Chloroisoquinoline
Packaging of 1-Chloroisoquinoline
Industrial 1-Chloroisoquinoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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