Methyl 4-amino-3-iodobenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 19718-49-1 |
| Product name | Methyl 4-amino-3-iodobenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 4-amino-3-iodobenzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 4-amino-3-iodobenzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 4-amino-3-iodobenzoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing antithyroid drugs (e.g., mercaptomethylazole derivatives) | Prepared via esterification and functional group transformation of iodoanilines to yield target drug molecules |
| Organic Synthesis | Substrate for coupling reactions to construct iodinated aryl frameworks (e.g., Suzuki, Heck reactions) | Participates in palladium-catalyzed cross-coupling as a haloarene; iodine is either retained or removed after introduction of substituents |
| Materials Science | Functionalized precursor for liquid crystal monomers and organic optoelectronic materials | After diazotization–iodination or direct iodination, coupled with cyanophenyl/alkoxyphenyl rings to form liquid crystal core structures |
Manufacturing Quality Control of Methyl 4-amino-3-iodobenzoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., starting materials, intermediates, dehalogenated or hydrolyzed products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, DMF, dichloromethane) based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water; endpoint detected amperometrically. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Ni, Fe) after acid digestion, based on atomic emission intensities at characteristic wavelengths. |
| Iodine Content | Potentiometric Titration with Silver Nitrate | Titration with AgNO3 solution using a silver indicator electrode; endpoint determined by potential inflection due to AgI precipitation. |
| Acid Value | Acid-Base Titration | Neutralization of free carboxylic acid groups with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid phase transition range using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against defined standards. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under specified temperature and vacuum conditions, reflecting volatile content including residual solvents and moisture. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection after sample dissolution and filtration. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of palladium (from catalytic hydrogenation steps) following microwave-assisted acid digestion and isotopic mass detection. |
Technical Specifications of Methyl 4-amino-3-iodobenzoate
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 4-amino-3-iodobenzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 4-amino-3-iodobenzoate
Safety Information of Methyl 4-amino-3-iodobenzoate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 4-amino-3-iodobenzoate
Industrial Methyl 4-amino-3-iodobenzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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