China Factory Direct
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| CAS number | 198477-89-3 |
| Product name | 1-(5-BROMO-2-FLUOROPHENYL)ETHANONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate synthesis | Used in the synthesis of active pharmaceutical ingredients (APIs), such as protein kinase inhibitors, to construct target molecular frameworks via Suzuki coupling, reductive amination, and related reactions |
| Organic synthesis | Synthetic building block | As a fluorinated aromatic ketone, participates in multistep organic transformations, including halogen-directed metallation and nucleophilic addition |
| Agricultural chemicals | Potential intermediate | Applied in the development of novel fluorinated agrochemical molecules, serving as a structural modification unit to introduce specific biological activity profiles |
| Test Item | Common Testing Method | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and state (e.g., white to pale yellow crystalline or powder) to determine if it meets the standard description. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with a UV detector (e.g., 254 nm), and calculate the purity of the main component using peak area normalization or external standard method. |
| Content Determination | HPLC External Standard Method / Gas Chromatography (GC, if applicable) | Establish a calibration curve using a known concentration of standard material to quantitatively determine the target compound content, usually requiring ≥98.0%. |
| Related Substances/Impurities | HPLC Gradient Elution Method | Separate potential process impurities and degradation products through gradient elution, setting impurity limits (e.g., single impurity ≤0.5%, total impurities ≤1.0%). |
| Moisture | Karl Fischer Titration | Determine moisture content in the sample using potentiometric or volumetric titration, controlled within specified limits (e.g., ≤0.5%). |
| Residual Solvents | Gas Chromatography Headspace Method (GC-HS) | According to ICH Q3C guidelines, detect organic solvents potentially remaining from synthesis (e.g., methanol, ethyl acetate, dichloromethane, etc.). |
| Melting Point | Capillary Melting Point Apparatus | Determine the melting temperature range of the compound (e.g., literature value about 75–78°C), used for preliminary identification and purity evaluation. |
| Structure Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | Confirm hydrogen and carbon framework using ¹H-NMR and ¹³C-NMR; verify functional groups using IR; determine molecular weight using MS for comprehensive structural confirmation. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect total amounts of heavy metals such as lead, cadmium, mercury, and arsenic according to pharmacopoeia methods, typically requiring ≤20 ppm. |
| Loss on Drying | Oven Drying Method | Dry to constant weight at a certain temperature (e.g., 105°C) to measure the loss of volatile substances, assessing stability and water content. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.