China Factory Direct
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| CAS number | 198545-46-9 |
| Product name | FMOC-D-2-Fluorophe |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As a non-natural amino acid derivative for peptide drug synthesis and modification | Used in solid-phase or solution-phase peptide synthesis |
| Biochemistry | For protein structural studies or enzyme substrate design | Applied in bioconjugation or labeling techniques |
| Materials Science | As a chiral building block in the synthesis of functional materials (e.g., MOFs) | Employed in crystal engineering or self-assembly processes |
| Academic Research | As a reagent in asymmetric catalysis or organic synthetic methodology development | Used in catalytic reactions or organic synthesis experiments |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies FMOC-D-2-fluorophenylalanine by UV absorbance at 265 nm using a reversed-phase C18 column and gradient elution with aqueous acetonitrile. |
| Chiral Purity | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase (e.g., Chirobiotic T) and quantifies enantiomeric excess via UV detection. |
| Residual Solvents | GC-FID | Detects and quantifies residual solvents (e.g., DMF, dichloromethane, methanol) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water by coulometric or volumetric titration with iodine generated electrochemically in presence of pyridine/methanol. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion by detecting metal isotopes via mass spectrometry. |
| Residual Palladium | ICP-OES | Determines palladium content from catalytic hydrogenation residues using plasma optical emission spectroscopy after microwave digestion. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., deprotected amino acid, dipeptide, FMOC-OH) using stability-indicating gradient HPLC. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using a polarimeter to confirm chiral identity and batch consistency. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition as indicator of crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular scattering intensity of laser light. |
| Loss on Drying | Gravimetric Heating | Determines volatile content by measuring weight loss after heating at 105 C under vacuum for 2 hours. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | +43.0 to +45.0 deg (c=1, in DMF) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.