FMOC-L-2-Chlorophe Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 198560-41-7 |
| Product name | FMOC-L-2-Chlorophe |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-L-2-Chlorophe
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-L-2-Chlorophe Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-L-2-Chlorophe
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral amino acid protecting monomers for solid-phase peptide synthesis (SPPS) | Used as Fmoc-protected non-natural amino acid monomers to synthesize therapeutic peptides or peptidomimetics containing 2-chlorophenylalanine residues, with peptide chain elongation on resin via standard piperidine deprotection–coupling cycles |
| Biochemical Research | Construction of structurally modified peptide probes or enzyme inhibitors | Employed for site-specific incorporation of chloroaryl side chains to enhance hydrophobicity, modulate conformation, or improve target binding affinity; commonly coupled with HATU/DIPEA activation for amide bond formation |
| Materials Science | Building blocks for functionalized peptide-based nanomaterials | Applied as building modules bearing aromatic halogen functionality to enable subsequent palladium-catalyzed cross-coupling reactions (e.g., Suzuki or Heck reactions), facilitating postsynthetic modification and functional integration on peptide surfaces |
Manufacturing Quality Control of FMOC-L-2-Chlorophe
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 268 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., DMF, DCM, methanol) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via electrochemical reaction stoichiometry. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 degrees C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, As, Hg) using inductively coupled plasma mass spectrometry with isotope dilution calibration. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to detect endpoint based on change in potential due to AgCl precipitation. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after high-temperature ashing (700-800 degrees C) to determine inorganic ash content as sulfate or metal oxide. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser light scattering to determine D10, D50, D90 values per ISO 13320. |
| Microbial Contamination | Membrane Filtration | Filtration of solution followed by incubation on TSA and SDA media to enumerate aerobic bacteria and fungi per USP <61>. |
| pH of Solution | pH Meter | Measurement of hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode pH meter. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant eutectic impurities. |
Technical Specifications of FMOC-L-2-Chlorophe
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -47 to -45° (c=1, in DMF) |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-L-2-Chlorophe
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-L-2-Chlorophe
Packaging of FMOC-L-2-Chlorophe
Industrial FMOC-L-2-Chlorophe Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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