Fmoc-3-chloro-L-phenylalanine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 198560-44-0 |
| Product name | Fmoc-3-chloro-L-phenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-3-chloro-L-phenylalanine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-3-chloro-L-phenylalanine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-3-chloro-L-phenylalanine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as an amino acid derivative for protecting groups in peptide synthesis | Applied in solid-phase peptide synthesis (SPPS) via the Fmoc strategy to incorporate N-Fmoc-L-3-chlorophenylalanine, enabling controlled assembly of peptides with chlorophenyl-modified side chains |
| Chemical Synthesis | Used as a template for constructing non-natural amino acids containing chloroaromatic structures | Employed as a chiral building block in multistep organic synthesis to construct biologically active chlorophenylalanine derivatives |
| Biochemical Research | Used as a probe molecule for studying protein structure and function | Site-specifically incorporated into proteins to support photo-crosslinking, fluorescent labeling, or conformational stability studies |
Manufacturing Quality Control of Fmoc-3-chloro-L-phenylalanine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 265 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; L-isomer quantified relative to D-isomer using UV detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., DMF, dichloromethane) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration where iodine reacts stoichiometrically with water in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification after acid digestion, using isotopic dilution or external calibration for elements like Pb, Cd, Hg, As. |
| Residual Chloride | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deprotected amine, hydrolyzed by-products) using gradient reverse-phase HPLC. |
| Optical Rotation | [alpha]D Measurement | Specific rotation measured at 20 deg C using sodium D-line (589 nm) in specified solvent (e.g., 1% w/v in DMF), confirming chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change; used to verify identity and detect gross impurities. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under controlled temperature and vacuum; indicates volatile content including residual solvents and moisture. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity against established reference standards under controlled lighting conditions. |
| pH of Solution | pH Meter | Measurement of aqueous suspension (e.g., 1% w/v) using calibrated pH electrode to assess acidic/basic degradation products. |
Technical Specifications of Fmoc-3-chloro-L-phenylalanine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -32.0 ± 2.0° (c=1, in DMF) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-3-chloro-L-phenylalanine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-3-chloro-L-phenylalanine
Safety Information of Fmoc-3-chloro-L-phenylalanine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Fmoc-3-chloro-L-phenylalanine
Industrial Fmoc-3-chloro-L-phenylalanine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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