Fmoc-N-methyl-O-benzyl-L-threonine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 198561-81-8 |
| Product name | Fmoc-N-methyl-O-benzyl-L-threonine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-N-methyl-O-benzyl-L-threonine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-N-methyl-O-benzyl-L-threonine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-N-methyl-O-benzyl-L-threonine
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical intermediates | Used as a chiral building block for synthesizing peptides and threonine-containing active pharmaceutical ingredients (APIs) |
| Peptide Synthesis | Solid-phase peptide synthesis (SPPS) | The Fmoc protecting group can be removed under mild basic conditions, enabling coupling reactions in solid-phase synthesis |
| Chemical Synthesis | Chiral synthetic reagent | Provides an optically pure threonine scaffold for asymmetric synthesis and stereoselective reactions |
| Biotechnology | Antibody–drug conjugate (ADC) development | Applied in constructing linker structures to enable site-specific conjugation of drugs to antibodies via defined peptide sequences |
| Materials Science | Intermediate for functional material synthesis | Used to construct peptide-based materials with defined secondary structures or self-assembling molecular systems |
| Analytical Chemistry | Reference standard or control substance | Serves as a reference material in analytical testing for quality control and structural confirmation |
| Biopharmaceuticals | Enzyme substrate or inhibitor studies | Applied in studying substrate specificity of proteases and peptidases, or as a basis for designing enzyme inhibitors |
| Organic Chemistry | Research on C–H activation or coupling reactions | Used as a multifunctional molecule bearing a benzylic protecting group in transition metal-catalyzed coupling reaction studies |
Manufacturing Quality Control of Fmoc-N-methyl-O-benzyl-L-threonine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 260-280 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess assessment via separation on a chiral stationary phase with UV detection, using a validated chiral column and mobile phase. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the reaction of iodine with water in a controlled anhydrous medium. |
| Residual Solvents | GC-FID | Identification and quantification of common organic solvents (e.g., DMF, THF, methanol) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residual Chloride | Ion Chromatography | Quantitative analysis of chloride ions using suppressed conductivity detection after anion exchange separation. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under controlled temperature and vacuum conditions, reflecting volatile impurities and moisture. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and identity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection by observing solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deprotected forms, diastereomers) using gradient reverse-phase HPLC. |
| Residual Benzyl Alcohol | GC-FID | Targeted quantification of benzyl alcohol (a potential degradation product or synthesis residue) by gas chromatography with FID. |
| pH of Solution | Potentiometric pH Measurement | Determination of aqueous slurry or solution pH using calibrated glass electrode and pH meter. |
Technical Specifications of Fmoc-N-methyl-O-benzyl-L-threonine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148°C - 152°C |
| Optical Rotation | -23° to -27° (c=1, in DMF) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-N-methyl-O-benzyl-L-threonine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-N-methyl-O-benzyl-L-threonine
Safety Information of Fmoc-N-methyl-O-benzyl-L-threonine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Fmoc-N-methyl-O-benzyl-L-threonine
Industrial Fmoc-N-methyl-O-benzyl-L-threonine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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