China Factory Direct
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| CAS number | 19883-78-4 |
| Product name | 2-FLUORO-L-PHENYLALANINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing peptide-based therapeutics and radiotracers, used in developing PET (positron emission tomography) imaging agents | Introduced as a fluorinated amino acid building block via solid-phase or solution-phase peptide synthesis to construct radiolabeled probes targeting tumors or neuronal receptors |
| Biotechnology | Insertion of non-canonical amino acids in protein engineering and enzymatic functional studies | Genetically encoded incorporation of L-2-fluorophenylalanine into recombinant proteins at defined positions using genetic code expansion to investigate structure–function relationships |
| Agrochemical R&D | Building block for fluorinated agrochemical molecules | Integrated into the active molecular scaffold via organic synthesis to enhance metabolic stability and biological activity |
| Chemical Research | Chiral fluorinated building block for asymmetric synthesis | Used in transition metal-catalyzed or enzyme-catalyzed asymmetric reactions to construct optically active fluorinated compounds |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Optical Rotation | Polarimetry | Measurement of the angle of rotation of plane-polarized light induced by chiral molecules in solution at specified concentration, path length, and temperature. |
| Enantiomeric Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase; quantification based on relative peak areas. |
| Loss on Drying | Gravimetric (105 C oven) | Mass loss determined after drying a sample at 105 C to constant weight, reflecting volatile content including residual solvents and moisture. |
| Residual Solvents | GC-FID | Identification and quantification of common organic solvents (e.g., methanol, acetone, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of heavy metals (Pb, Cd, As, Hg, Ni) after acid digestion, based on atomic emission intensities. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric (500-600 C) | Residue mass after incineration at high temperature following sulfuric acid treatment, indicating inorganic impurities. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent; water reacts stoichiometrically to determine trace moisture content. |
| Related Substances | HPLC-UV (Gradient) | Detection and quantification of structurally related impurities (e.g., deaminated, decarboxylated, or fluorinated analogs) using gradient elution and UV detection. |
| pH (1% aqueous solution) | Potentiometric (pH meter) | Measurement of hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode. |
| Microbial Limits | Membrane Filtration / TSA/SDA | Enumeration of aerobic mesophilic bacteria and fungi via membrane filtration followed by incubation on Tryptic Soy Agar and Sabouraud Dextrose Agar. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 245-249°C |
| Optical Rotation | -12.0 to -18.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.