1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 199336-83-9 |
| Product name | 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 199336-83-9
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 199336-83-9 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 199336-83-9
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate | Used as a chiral building block or intermediate in the synthesis of certain pharmaceuticals, including antidepressants and drugs for neurodegenerative disorders |
| Chemical R&D | Research | Employed as a chiral building block for synthesizing other complex molecules, particularly in organic synthesis research |
| Biopharmaceuticals | Synthesis of bioactive molecules | Applied as a chiral source in the synthesis of bioactive molecules, especially where specific stereochemical configurations are required |
Manufacturing Quality Control of 199336-83-9
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation and quantification of (R)- and (S)-enantiomers on a chiral stationary phase, calculating ee from peak area ratio. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., MeOH, EtOAc, THF, heptane) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, achieving sub-pptr detection limits. |
| Residual Palladium | ICP-MS | Specific quantification of Pd residues (common from asymmetric hydrogenation catalysts) following microwave-assisted digestion. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions in solution, calibrated against NaCl standards. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment against water-white standard; quantitative color measurement via spectrophotometric APHA scale. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate. |
| Specific Optical Rotation | [α]D Measurement | Determination of chiral compound’s rotation of plane-polarized light at 589 nm, confirming identity and enantiopurity. |
| Residual tert-Butyl Carbamate (Boc-OH) | HPLC-UV | Separate and quantify unreacted Boc-anhydride hydrolysis product using reverse-phase HPLC with UV detection. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Identification and quantification of process-related impurities and degradation products under stress conditions (acid/base/oxidative/thermal). |
Technical Specifications of 199336-83-9
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | [α]D20 = +25.0° to +29.0° (c=1.0 in CHCl3) |
| Total Impurities | <=2.0% (GC-MS) |
| Single Impurity | <=0.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic mild organic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 199336-83-9
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 199336-83-9
Packaging of 199336-83-9
Industrial 199336-83-9 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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