1-Bromo-4-chloro-2-fluorobenzene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1996-29-8 |
| Product name | 1-Bromo-4-chloro-2-fluorobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeElectronic GradeMaterial GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Bromo-4-chloro-2-fluorobenzene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Bromo-4-chloro-2-fluorobenzene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Bromo-4-chloro-2-fluorobenzene
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor agents and antibiotic intermediates | Used as a substrate in aromatic nucleophilic substitution reactions to construct complex molecular frameworks via substitution with amines, alcohols, and other nucleophiles |
| Agrochemicals | Synthesis of herbicide and insecticide intermediates | Applied in halogen exchange or coupling reactions to introduce fluorochlorophenyl moieties, enhancing biological activity |
| Dyes & Pigments | Synthesis of specialty fluorescent dyes and organic pigments | Employed as an aromatic core within conjugated systems, participating in diazotization, condensation, and related reactions |
| Electronic Materials | Preparation of organic semiconductor and OLED material intermediates | Utilized in Suzuki, Ullmann, and other coupling reactions to build aromatic conjugated structures |
| Chemical Reagents | Starting material for synthesizing other fluorochlorobenzene derivatives | Subjected to functional group transformations via metal-catalyzed cross-coupling and nucleophilic substitution reactions |
Manufacturing Quality Control of 1-Bromo-4-chloro-2-fluorobenzene
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Characteristics | Visual Inspection + Physical Property Measurement | Observe the color and state of the sample (usually a colorless to light yellow liquid), measure physical parameters such as boiling point, density, and refractive index, ensuring compliance with pharmacopoeia or enterprise standards. |
| Purity (Main Component Content) | Gas Chromatography (GC) | Use capillary chromatographic columns (e.g., DB-5 or HP-5) with an FID detector. Quantify using internal or external standard methods by measuring the peak area of 1-bromo-4-chloro-2-fluorobenzene. The content is typically required to be ≥98.0%. |
| Impurity Profile Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | On the basis of GC separation, use mass spectrometry to identify residual solvents and by-products (such as dibromo/dichlorobenzene isomers and unreacted raw materials), achieving qualitative and semi-quantitative analysis. |
| Halogen Element Content | Combustion Ion Chromatography (CIC) or Bomb Combustion + Ion Chromatography | After combustion in an oxygen bomb, halogens are converted into halide ions. Use ion chromatography to determine Br⁻, Cl⁻, and F⁻ concentrations, verifying whether the elemental composition conforms to the molecular formula. |
| Moisture Content | Karl Fischer Titration | Determine trace moisture content using coulometric or volumetric methods, ensuring moisture content is below 0.1%–0.5%, to avoid hydrolysis or interference in subsequent reactions. |
| Solvent Residue | Headspace-Gas Chromatography (HS-GC) | For organic solvents possibly remaining from production (e.g., toluene, acetonitrile, DMF), use headspace sampling with GC-FID detection, complying with ICH Q3C standards. |
| UV Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measure absorption peaks at specific wavelengths (e.g., 220–280 nm) for rapid identification and preliminary purity assessment (must be combined with other methods for confirmation). |
| Melting Point/Boiling Point | Capillary Melting Point Apparatus / Boiling Point Apparatus | Determine the boiling point (approximately 220–225°C) as a reference physical constant, assisting in identification and purity evaluation. |
| Heavy Metal Residue | Atomic Absorption Spectrometry (AAS) or ICP-MS | After digestion of the sample, detect heavy metals such as Pb, Cd, Hg, and As, ensuring compliance with pharmaceutical or electronic-grade raw material standards (e.g., ≤10 ppm). |
Technical Specifications of 1-Bromo-4-chloro-2-fluorobenzene
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Refractive Index (n20/D) | 1.535–1.545 |
| Relative Density (20°C/4°C) | 1.52–1.54 g/cm³ |
| Odor | Characteristic aromatic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Bromo-4-chloro-2-fluorobenzene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Bromo-4-chloro-2-fluorobenzene
Safety Information of 1-Bromo-4-chloro-2-fluorobenzene
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-Bromo-4-chloro-2-fluorobenzene
Industrial 1-Bromo-4-chloro-2-fluorobenzene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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