China Factory Direct
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| CAS number | 19962-37-9 |
| Product name | N-2-Acetylguanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Intermediate in nucleotide metabolism studies; used to synthesize modified nucleoside analogs | Prepared via selective N-2 acetylation of guanine with acetyl chloride or acetic anhydride under basic conditions |
| Pharmaceutical R&D | Used to construct purine derivative libraries for screening antiviral or anticancer compounds | Acetylation conducted under controlled low-temperature conditions in anhydrous solvent, using DMAP as catalyst and acetic anhydride as acetylating agent |
| Analytical Chemistry | Reference standard for HPLC/MS detection of purine metabolites in biological samples | Purified to high purity by crystallization and verified by NMR and mass spectrometry for quantitative analytical reference |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies N-2-acetylguanine by reversed-phase HPLC with UV detection at 254 nm, using external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., guanine, N-2-acetyl-6-chloroguanine) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., methanol, acetone, ethyl acetate) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration based on iodine consumption in pyridine/methanol medium. |
| Heavy Metals | ICP-OES | Quantifies total heavy metals (Pb, Cd, Hg, As, Ni) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures non-volatile inorganic residue after combustion with sulfuric acid treatment and high-temperature ignition. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical characteristics (color, homogeneity, presence of foreign particles) against established reference standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry or dispersed state using Mie scattering theory and optical diffraction patterns. |
| pH of Aqueous Suspension | pH Meter | Determines pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per USP <791>. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 278-282°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.