N-METHYL-L-PROLINE MONOHYDRATE 98 Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 199917-42-5 |
| Product name | N-METHYL-L-PROLINE MONOHYDRATE 98 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-METHYL-L-PROLINE MONOHYDRATE 98
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-METHYL-L-PROLINE MONOHYDRATE 98 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-METHYL-L-PROLINE MONOHYDRATE 98
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral auxiliaries; ligands for asymmetric synthesis catalysts | Used to construct chiral centers and regulate stereoselectivity as ligands in palladium-catalyzed cross-coupling reactions |
| Organic Synthesis | Chiral building blocks; intermediates | Employed in peptide modification and drug molecule structural optimization, such as introduction of side chains in antitumor compounds |
| Biochemical Research | Enzyme inhibitor probes; tools for protein–protein interaction studies | N-methylation applied to enhance metabolic stability for structure–activity relationship (SAR) analysis |
Manufacturing Quality Control of N-METHYL-L-PROLINE MONOHYDRATE 98
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantitative determination using reverse-phase HPLC and UV absorbance at 200-220 nm, calibrated against certified reference standard. |
| Water Content | Karl Fischer titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in methanol-based solvent system. |
| Optical Rotation | [alpha]D measurement | Measurement of specific rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., methanol, acetone) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Anion exchange separation and conductivity detection of chloride ions in aqueous solution. |
| Sulfate Impurity | Ion Chromatography | Anion exchange separation and conductivity detection of sulfate ions in aqueous solution. |
| Related Substances | HPLC with UV detection | Identification and quantification of structurally similar impurities using gradient reverse-phase HPLC and UV detection. |
| pH (1% w/v aqueous solution) | Potentiometric pH measurement | Determination of hydrogen ion activity using calibrated glass electrode in a standardized aqueous solution. |
| Loss on Drying | Gravimetric analysis | Mass loss measured after drying under controlled temperature and vacuum to determine volatile content excluding water. |
| Microbial Contamination | Membrane filtration and plate count | Quantitative enumeration of aerobic mesophilic microorganisms following USP <61> and ISO 11731. |
| Particle Size Distribution | Laser diffraction | Analysis of dry powder particle size distribution based on light scattering patterns generated by dispersed particles in air. |
Technical Specifications of N-METHYL-L-PROLINE MONOHYDRATE 98
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Optical Rotation | -83.1° ± 3.0° (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-METHYL-L-PROLINE MONOHYDRATE 98
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of N-METHYL-L-PROLINE MONOHYDRATE 98
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-METHYL-L-PROLINE MONOHYDRATE 98
Industrial N-METHYL-L-PROLINE MONOHYDRATE 98 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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