Z-D-ASN(TRT)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 200259-87-6 |
| Product name | Z-D-ASN(TRT)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Z-D-ASN(TRT)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-D-ASN(TRT)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-D-ASN(TRT)-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a protective intermediate in peptide synthesis to construct complex peptide chains containing asparagine residues | Applied in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS), where the benzyloxycarbonyl (Z) group protects the α-amino group and the trityl (Trt) group protects the side-chain amide nitrogen, minimizing side reactions and enhancing selectivity |
| Biochemical Research | Used to synthesize specifically modified asparagine derivatives for studying protein structure–function relationships | Trt deprotection under mild acidic conditions while retaining the Z group for subsequent coupling steps; commonly applied in the synthesis of enzyme inhibitors or probe molecules |
Manufacturing Quality Control of Z-D-ASN(TRT)-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., deprotection products, diastereomers, hydrolysis by-products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of residual solvents (e.g., DMF, THF, methanol, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of water with iodine and sulfur dioxide in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions eluted from an anion-exchange column after sample dissolution and filtration. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20-25 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Residual Palladium | ICP-OES | Quantification of palladium residues (e.g., from Pd-catalyzed coupling steps) after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed particles to determine D10, D50, D90 values based on light scattering intensity vs. angle. |
| Loss on Drying | Gravimetric Analysis | Mass loss measurement after drying under controlled temperature and vacuum conditions to assess volatile content and residual solvents. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Residual Benzyl Chloride | GC-MS | Selective identification and quantification of benzyl chloride (a potential alkylating impurity) using gas chromatography coupled with mass spectrometric detection. |
Technical Specifications of Z-D-ASN(TRT)-OH
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Optical Rotation | +18.0 to +22.0° (c=1, DMF) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Z-D-ASN(TRT)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-D-ASN(TRT)-OH
Packaging of Z-D-ASN(TRT)-OH
Industrial Z-D-ASN(TRT)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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