China Factory Direct
|
|
| CAS number | 2004-06-0 |
| Product name | 6-Chloropurine ribonucleoside |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate or precursor compound for antiviral and anticancer drugs | Used in the synthesis of nucleoside analogs, such as purine antimetabolites including clofarabine |
| Biochemical Research | Studying RNA modifications, enzyme inhibition, and nucleoside metabolic pathways | Employed as a tool compound in in vitro enzymatic assays or metabolic interference experiments in cell culture |
| Pharmaceutical Manufacturing | Key starting material for synthesizing specific purine nucleoside derivatives | Structurally modified via chemical or enzymatic methods to introduce functional groups that enhance pharmacological activity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 260 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and control of known process-related and degradation impurities. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, acetone, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of toxic elements (e.g., Pb, Cd, Hg, As) at sub-ppb levels. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Optical Rotation | [alpha]D Measurement | Polarimetric measurement at 589 nm to confirm stereochemical integrity and enantiomeric purity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Direct pH measurement of a defined aqueous suspension or solution using calibrated pH electrode. |
| Residue on Ignition | Gravimetric Analysis | Weight loss after high-temperature ashing to determine inorganic residue content. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms via membrane filtration followed by incubation on soybean-casein digest agar. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using laser diffraction principle and Mie scattering theory. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, indicating crystallinity and purity. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 215-219°C |
| Optical Rotation | -44° to -42° (c=1, in water) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.