N-Fmoc-N'-trityl-D-glutamine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 200623-62-7 |
| Product name | N-Fmoc-N'-trityl-D-glutamine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Fmoc-N'-trityl-D-glutamine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Fmoc-N'-trityl-D-glutamine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Fmoc-N'-trityl-D-glutamine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for peptide synthesis | Used in solid-phase or solution-phase peptide synthesis as a protected glutamine derivative, with dual Fmoc and trityl protection of the amino group and side chain to enhance coupling selectivity and yield |
| Biotechnology | Protein engineering and modification | Provides structural stability and chemical compatibility during synthesis of functional peptides or labeled proteins with defined sequences |
| Organic synthesis | Construction of complex peptide molecules | Serves as a building block in stepwise coupling reactions for synthesizing long-chain or cyclic peptides, compatible with the Fmoc/tBu strategy |
Manufacturing Quality Control of N-Fmoc-N'-trityl-D-glutamine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a reference standard using reversed-phase chromatography and UV detection at 268 nm. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase with UV detection; D-isomer content calculated relative to total glutamine peak. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, DCM, methanol) using capillary column gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol buffer system. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion and dilution, using inductively coupled plasma mass spectrometry. |
| Residual Triphenylmethanol | HPLC-UV | Quantitative determination of triphenylmethanol impurity by reversed-phase HPLC with UV detection at 254 nm. |
| Residual Fmoc-Cl | GC-MS | Detection and quantification of unreacted Fmoc chloride by gas chromatography coupled with mass spectrometric identification and calibration. |
| Acid Value | Acid-Base Titration | Determination of free carboxylic acid groups via titration with standardized NaOH solution using phenolphthalein indicator. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of particulates or foreign matter under controlled white light against established reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Measurement of temperature range over which solid transitions to liquid, using calibrated digital melting point instrument with ramp rate of 1 C/min. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution by measuring angular variation in intensity of laser light scattered by dispersed particles. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) following ISO 11731-based filtration and culture. |
Technical Specifications of N-Fmoc-N'-trityl-D-glutamine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +13.0° to +14.0° (c=1, DMF) |
| Melting Point | 178°C to 182°C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Fmoc-N'-trityl-D-glutamine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Fmoc-N'-trityl-D-glutamine
Packaging of N-Fmoc-N'-trityl-D-glutamine
Industrial N-Fmoc-N'-trityl-D-glutamine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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