trans-4-fluoro-3-hydroxypyrrolidine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2006333-41-9 |
| Product name | trans-4-fluoro-3-hydroxypyrrolidine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for trans-4-fluoro-3-hydroxypyrrolidine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk trans-4-fluoro-3-hydroxypyrrolidine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of trans-4-fluoro-3-hydroxypyrrolidine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Used in the synthesis of pharmaceutical molecules, particularly those requiring fluorinated and hydroxyl structural motifs |
| Medical Research | Biological Activity Studies | Employed as a tool compound to investigate the mechanism of action at specific biological targets |
| Materials Science | Synthesis of High-Performance Polymers | Applied as a monomer or crosslinker to enhance mechanical properties and thermal stability |
| Chemical Synthesis | Organic Synthesis | Utilized as a chiral catalyst or chiral auxiliary in asymmetric synthesis |
Manufacturing Quality Control of trans-4-fluoro-3-hydroxypyrrolidine hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and reporting of any impurity >0.1%. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Residual Solvents | GC-FID | Detection and quantification of common solvents (e.g., methanol, acetone, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, Ni) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Content | Potentiometric Titration | Direct titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration in aqueous solution. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by ignition at 600-750 C followed by weighing of residual residue. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry powder particle size distribution using laser scattering principles and Mie theory. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
| pH (1% w/v aqueous solution) | pH Meter | Electrometric measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated pH electrode. |
| Identity Confirmation | FTIR Spectroscopy | Comparison of sample infrared absorption spectrum with reference standard to verify functional group and structural fingerprint. |
Technical Specifications of trans-4-fluoro-3-hydroxypyrrolidine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 162.0–166.0°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Optical Rotation | -15.0° to -19.0° (c=1, in methanol) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of trans-4-fluoro-3-hydroxypyrrolidine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of trans-4-fluoro-3-hydroxypyrrolidine hydrochloride
Safety Information of trans-4-fluoro-3-hydroxypyrrolidine hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of trans-4-fluoro-3-hydroxypyrrolidine hydrochloride
Industrial trans-4-fluoro-3-hydroxypyrrolidine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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