China Factory Direct
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| CAS number | 201473-90-7 |
| Product name | FMOC-DAP(FMOC)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Doubly protected amino acid monomer for solid-phase peptide synthesis (SPPS) | Used to synthesize peptides containing multiple lysine or arginine residues, enabling selective deprotection and coupling via the Fmoc strategy; target peptide chains are assembled stepwise on resin |
| Pharmaceutical R&D | Building block for novel therapeutic peptides, including antitumor, antiviral, and targeted protein degradation agents (e.g., PROTACs) | Serves as a key building block in automated peptide synthesizers, participating in sequential condensation reactions under orthogonal protection schemes (e.g., used in conjunction with Fmoc-Lys(Boc)-OH) |
| Biomaterials | Design of degradable peptide hydrogels and biomimetic extracellular matrix scaffolds | After incorporation into specific sequences via solid-phase synthesis, the Fmoc group is removed with piperidine and the peptide is cleaved from the resin using TFA, followed by purification to yield a peptide precursor with precise primary structure for subsequent crosslinking or self-assembly |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification by reverse-phase HPLC with UV detection at 265 nm using external standard calibration. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against reference standards or area normalization. |
| Residual Solvents | GC-FID | Detection and quantification of common solvents (e.g., DMF, DCM, MeOH) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 deg C with sodium D-line (589 nm). |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Ni, Pd) by inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of residual Pd from coupling catalysts using ICP-MS with internal standard correction. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under controlled temperature and vacuum conditions. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in suspension using Mie scattering theory. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms via membrane filtration followed by incubation on agar media. |
| pH of Aqueous Suspension | Potentiometric Titration | Measurement of pH in a defined aqueous suspension using calibrated glass electrode. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 245–249 °C |
| Optical Rotation | -15.0 to -9.0 deg (c=1, DMF) |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.