Fluorocytosine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2022-85-7 |
| Product name | Fluorocytosine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fluorocytosine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fluorocytosine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fluorocytosine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antifungal agent for systemic fungal infections, including cryptococcal meningitis and candidiasis | Administered orally or intravenously; metabolized in vivo to 5-fluorouracil to exert antifungal activity |
| Pharmaceuticals | Reference standard or metabolite precursor in anticancer drug research | Used as an analytical reference standard and quality control material in drug metabolism and pharmacokinetics (DMPK) studies |
| Research | Selective screening reagent in molecular biology and microbiology studies | Applied to generate uracil auxotrophic yeast or fungal mutant strains, enabling positive/negative selection on 5-FC-containing media |
Manufacturing Quality Control of Fluorocytosine
| Test Item | Commonly Used Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase column with phosphate buffer-methanol or acetonitrile as the mobile phase. The main component is quantified using a UV detector (e.g., 260 nm), offering high accuracy and good repeatability. |
| Related Substances / Impurity Testing | HPLC (Gradient Elution) | Optimized gradient program separates the main peak from potential impurities (e.g., degradation products, synthetic by-products). Impurity peaks are identified using a DAD detector and quantified by peak area normalization or external standard method. |
| Loss on Drying | Oven Drying Method (105°C to Constant Weight) | Sample is dried at 105°C until constant weight. The percentage of mass loss is calculated to evaluate moisture and volatile content, meeting pharmacopoeia-specified limits. |
| Residue on Ignition | High-Temperature Ashing Method (Muffle Furnace, 600–800°C) | Sample is ignited at high temperature and the remaining inorganic residue is weighed. Used to control inorganic impurities (e.g., metal catalyst residues), typically limited to ≤0.1%. |
| Heavy Metals Testing | Thioacetamide Method / ICP-MS | The Chinese Pharmacopoeia thioacetamide colorimetric method is used to detect lead, mercury, cadmium, etc. Alternatively, ICP-MS can be used for multi-element trace analysis, offering higher sensitivity. |
| Solution Clarity and Color | Visual Comparison Method / Colorimeter | Sample is dissolved in the specified solvent and compared with standard color solutions or measured using an instrument to ensure no visible discoloration or turbidity, meeting requirements for injectables or oral formulations. |
| pH Value | pH Meter Method | A solution of specified concentration is prepared and the pH is measured using a calibrated pH meter. Ensures acidity or alkalinity remains within the specified range (e.g., 4.0–6.0), guaranteeing stability and safety. |
| Residual Solvents | Gas Chromatography (GC-FID / HS-GC) | Headspace or direct injection GC is used to detect residual organic solvents (e.g., ethanol, acetone, DMF) from the synthesis process, complying with ICH Q3C limits. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRPD) | Crystal form consistency is confirmed through characteristic diffraction patterns, preventing changes in solubility or bioavailability due to polymorphism. |
| Microbial Limit Testing | Pour Plate Method / Membrane Filtration Method | Tests for total aerobic microbial count, mold, yeast count, and specified control organisms (e.g., Escherichia coli) as per pharmacopoeia requirements, ensuring compliance for non-sterile pharmaceuticals. |
Technical Specifications of Fluorocytosine
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 234-238°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fluorocytosine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fluorocytosine
Packaging of Fluorocytosine
Industrial Fluorocytosine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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