China Factory Direct
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| CAS number | 20280-81-3 |
| Product name | 4-METHOXYCOUMARIN |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Anticoagulant drug intermediate (e.g., warfarin synthesis) | Condensed with ethyl chloroacetate under alkaline conditions, followed by hydrolysis and cyclization to produce warfarin |
| Fine Fragrances | Fixative and component of food flavorings (with hay- and lavender-like odor) | Directly incorporated into soap fragrances, detergent fragrances, and certain food flavorings at typical concentrations ≤10 ppm |
| Pesticides | Plant growth regulator and insecticide intermediate | Used to synthesize biologically active coumarin derivatives—such as via bromination or nitration—for agrochemical development |
| Organic Synthesis | Intermediate for fluorescent dyes and optical materials | Converted into coumarin-based fluorescent probes or OLED functional materials via Vilsmeier–Haack formylation or Pd-catalyzed cross-coupling reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 270-320 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., unreacted precursors, isomers, degradation products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, toluene) based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric determination of water via iodine-sulfur dioxide reaction in pyridine/methanol medium. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity-based detection of chloride ions using anion-exchange column and suppressed conductivity detector. |
| Sulfated Ash | Gravimetric Analysis | Residue mass after incineration at 600-750 C following sulfuric acid treatment, expressed as percentage of sample weight. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration under controlled lighting. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measured after heating at 105 C for 2 hours, reflecting volatile content including residual solvents and moisture. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light, confirming chiral integrity (though 4-methoxycoumarin is achiral, used for batch consistency). |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water), indicating acidic/basic impurities or hydrolysis products. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 185.0–189.0 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.