4-Bromo-3,5-difluoroaniline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 203302-95-8 |
| Product name | 4-Bromo-3,5-difluoroaniline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromo-3,5-difluoroaniline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromo-3,5-difluoroaniline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromo-3,5-difluoroaniline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antitumor agents (e.g., BTK inhibitors) | Used in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) |
| Pesticides | Structural building block for novel fluorinated insecticides and fungicides | Applied in nucleophilic substitution or diazotization-bromination reactions |
| Materials Science | Employed in the synthesis of high-performance liquid crystal materials and OLED hole-transport materials | Utilized in Ullmann condensation or copper-catalyzed amination reactions |
| Dyes & Pigments | Functionalized intermediate for fluorinated azo dyes, enhancing lightfastness and color fastness | Applied in diazotization-coupling reactions |
Manufacturing Quality Control of 4-Bromo-3,5-difluoroaniline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., isomers, residual halogenated precursors) via gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., DMF, THF, methanol) using capillary GC with flame ionization detection against calibration standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine generated electrochemically or added reagent, based on stoichiometric reaction with water. |
| Heavy Metals (as Pb) | ICP-OES | Measures total heavy metal content after acid digestion by detecting characteristic atomic emissions in inductively coupled plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particles or discoloration against established reference standards under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700–800 C) and weighing of the cooled crucible. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a saturated aqueous suspension (1:10 w/v) using calibrated pH electrode per USP <791>. |
| Bulk Density | Graduated Cylinder Method | Determines mass per unit volume by gently pouring sample into a calibrated cylinder and measuring settled volume after tapping. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution by analyzing angular variation in laser light scattering intensity from dispersed sample in liquid medium. |
Technical Specifications of 4-Bromo-3,5-difluoroaniline
| Test Item | Specification |
|---|---|
| Appearance | White crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 72–76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromo-3,5-difluoroaniline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromo-3,5-difluoroaniline
Packaging of 4-Bromo-3,5-difluoroaniline
Industrial 4-Bromo-3,5-difluoroaniline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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