China Factory Direct
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| CAS number | 2042-14-0 |
| Product name | 4-Methyl-3-nitrophenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Used in the synthesis of nonsteroidal anti-inflammatory drugs (e.g., etoricoxib) and other pharmaceutical molecules as an aromatic ring building block. |
| Agrochemical Industry | Intermediate | Used in the synthesis of active ingredients for herbicides, insecticides, and other agrochemicals; participates in arylations or reductive aminations. |
| Dye Industry | Dye Intermediate | Participates in coupling or condensation reactions for the synthesis of acid dyes, disperse dyes, and organic pigments. |
| Organic Synthesis | Functional Material Intermediate | Serves as a building block for synthesizing organic small molecules or polymer monomers with specialized optoelectronic properties. |
| Scientific Research | Reagent | Used as a reference standard or reaction substrate in developing novel organic synthetic methodologies and investigating chemical reaction mechanisms. |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity/Content Determination | High-Performance Liquid Chromatography (HPLC) | Reverse-phase C18 column is used with a mobile phase of methanol-water or acetonitrile-water. Detection is performed using a UV detector (typically at 254 nm or the maximum absorption wavelength). The content of 4-methyl-3-nitrophenol is calculated by external standard method or area normalization. This method offers excellent separation, high sensitivity, and good reproducibility, making it suitable for purity control of active pharmaceutical ingredients and intermediates. |
| Related Substances (Impurity) Testing | High-Performance Liquid Chromatography (HPLC) | Similar or optimized chromatographic conditions to those used in content determination are applied to separate and quantify potential organic impurities (such as unreacted starting materials, by-products, degradation products, etc.). Impurity peak areas are typically monitored against a threshold (e.g., 0.1%), aiding in assessing product purity and safety. |
| Melting Point Determination | Capillary Melting Point Method | Dried sample is packed into a capillary tube and heated at a specified rate in a melting point apparatus. The temperature range from initial melting to complete melting is recorded. The standard melting point of 4-methyl-3-nitrophenol is approximately 93–96 °C, with a narrow melting range indicating high purity. |
| Drying Loss | Drying Weight Loss Method | A known amount of sample is dried at 105 °C until constant weight is achieved. The percentage of mass loss is calculated to control moisture and other volatile components. Typically, drying loss should not exceed 0.5%. |
| Residue on Ignition | High-Temperature Ashing Method | The sample is ignited at high temperature (typically 700–800 °C) until constant weight is reached. The resulting residue (ash) is measured as a percentage of the original sample weight to assess inorganic impurities or catalyst residues. The typical limit is ≤0.1%. |
| Heavy Metals Testing | Thioacetamide Colorimetric Method (or ICP-MS) | According to Chinese Pharmacopoeia or relevant standards, thioacetamide is used under acidic conditions to generate hydrogen sulfide, which reacts with heavy metal ions to form colored precipitates for visual or instrumental quantification. Alternatively, Inductively Coupled Plasma Mass Spectrometry (ICP-MS) may be employed for highly sensitive detection of trace metal elements (e.g., Pb, As, Cd, Hg). |
| Appearance | Visual Inspection | Observe the sample's color (typically light yellow to pale brown crystalline or powder), odor, and physical state. It should conform to the standard description, with no visible foreign matter or clumping. |
| Test Item | Specification |
|---|---|
| Appearance | White to yellow to orange crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 72-76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.