FMOC-D-GLU(OALL)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 204251-33-2 |
| Product name | FMOC-D-GLU(OALL)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-D-GLU(OALL)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-D-GLU(OALL)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-D-GLU(OALL)-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthon for peptide-based drug synthesis | Used as a protected amino acid derivative in solid-phase peptide synthesis (SPPS): the Fmoc group protects the α-amino group, while the allyl ester provides temporary protection for the side-chain carboxyl group, enabling selective deprotection and coupling reactions |
| Biochemical Research | Construction of custom peptides containing D-glutamic acid residues | Palladium-catalyzed allyl ester deprotection to expose side-chain functional groups under mild conditions, supporting structure–activity relationship (SAR) studies or probe molecule synthesis |
| Organic Synthesis | Chiral building block for synthesis of non-natural amino acids and heterocyclic compounds | Participates in amidation, cyclization, and other reactions following Fmoc deprotection; the allyl ester enables cross-coupling and nucleophilic substitution transformations |
Manufacturing Quality Control of FMOC-D-GLU(OALL)-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 268 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., FMOC-D-Glu, diastereomers, hydrolysis products) via gradient HPLC-UV. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DCM, DMF, THF) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine generated electrochemically in pyridine-free reagent. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 20 C using sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Hg, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of Pd from allyl ester deprotection catalyst residues using isotope-dilution ICP-MS. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under vacuum at 40 C for 2 hours to determine volatile and moisture content. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
Technical Specifications of FMOC-D-GLU(OALL)-OH
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C - 132°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in DMF) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-D-GLU(OALL)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-D-GLU(OALL)-OH
Packaging of FMOC-D-GLU(OALL)-OH
Industrial FMOC-D-GLU(OALL)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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