Methyl 2-fluoro-4-iodobenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 204257-72-7 |
| Product name | Methyl 2-fluoro-4-iodobenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 2-fluoro-4-iodobenzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 2-fluoro-4-iodobenzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 2-fluoro-4-iodobenzoate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key pharmaceutical intermediate | Used in the synthesis of anticancer and targeted therapeutics, including protein kinase inhibitors and vascular endothelial growth factor receptor (VEGFR) inhibitors. |
| Agrochemicals | Agrochemical intermediate | Used in the synthesis of novel herbicides, fungicides, and other agrochemicals; employed to construct fluorinated and iodinated aryl heterocyclic structures. |
| Organic Synthesis | Coupling reagent | Leverages iodine’s reactivity in transition-metal-catalyzed coupling reactions—such as Suzuki, Stille, and Heck couplings—to form carbon–carbon bonds and prepare biaryl compounds. |
| Organic Synthesis | Functional group transformation building block | Exploits the reactivity of the ester group and fluorine atom to enable hydrolysis, reduction, or nucleophilic substitution, facilitating the synthesis of complex fluorinated aromatic derivatives. |
Manufacturing Quality Control of Methyl 2-fluoro-4-iodobenzoate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by retention time and UV response relative to main peak. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-OES | Determines total elemental metal impurities (e.g., Pb, Cd, Ni) by plasma excitation and atomic emission spectroscopy. |
| Iodine Content | Potentiometric Titration with Silver Nitrate | Quantifies iodide ions via argentometric titration using silver nitrate and potentiometric endpoint detection. |
| Acid Value | Acid-Base Titration | Measures carboxylic acid content by titration with standardized NaOH solution using phenolphthalein indicator. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Measures volatile matter loss by weighing sample before and after controlled heating at 105 C for 2 hours. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution by measuring angular variation in laser light scattering intensity. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride anions using suppressed conductivity detection after anion exchange separation. |
| Residual Palladium | ICP-MS | Detects trace palladium catalyst residues using inductively coupled plasma mass spectrometry with isotope-specific detection. |
Technical Specifications of Methyl 2-fluoro-4-iodobenzoate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 2-fluoro-4-iodobenzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 2-fluoro-4-iodobenzoate
Safety Information of Methyl 2-fluoro-4-iodobenzoate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 2-fluoro-4-iodobenzoate
Industrial Methyl 2-fluoro-4-iodobenzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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