(R)-N-Boc-3-pyrrolidineacetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 204688-60-8 |
| Product name | (R)-N-Boc-3-pyrrolidineacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-N-Boc-3-pyrrolidineacetic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-N-Boc-3-pyrrolidineacetic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-N-Boc-3-pyrrolidineacetic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an intermediate in the synthesis of biologically active compounds, including antitumor agents and antibiotics | Prepared via organic synthesis methods, such as acylation, reduction, and cyclization |
| Organic Synthesis | Employed to construct complex molecules containing the pyrrolidine structure | Processed through multi-step organic synthesis involving Boc protecting group installation and removal |
| Chemical Research | Utilized as a research reagent for developing novel pharmaceuticals or materials | Applied under varied reaction conditions and catalytic systems to explore its reactivity across different transformations |
Manufacturing Quality Control of (R)-N-Boc-3-pyrrolidineacetic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity (Enantiomeric Excess) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase; ee calculated from peak area ratio. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., THF, EtOAc, MeOH) using headspace GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residual Boc Chloride / tert-Butyl Carbonate | GC-MS | Detection and quantification of residual carbamate-forming agents via gas chromatography–mass spectrometry. |
| Acid Value | Potentiometric Titration | Neutralization of free carboxylic acid groups with standardized NaOH solution, monitored by pH electrode endpoint detection. |
| Optical Rotation | [α]D Measurement | Specific rotation determination at 589 nm (Na D-line) using a calibrated polarimeter in specified solvent/concentration. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed solid sample using Mie scattering theory to derive volumetric particle size distribution. |
| Residual Inorganic Salts (e.g., NaCl, K2CO3) | Ion Chromatography (IC) | Quantification of anions (Cl⁻, CO₃²⁻) and cations (Na⁺, K⁺) after aqueous extraction and separation on ion-exchange columns. |
| Microbial Contamination | Membrane Filtration & Plate Count | Enumeration of aerobic mesophilic microorganisms following filtration, membrane transfer to culture media, and colony counting after incubation. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment against water-white standard; color quantified by matching to APHA (Platinum-Cobalt) scale using colorimeter. |
| Melting Point | DSC | Thermal transition analysis by differential scanning calorimetry to determine onset and range of melting endotherm. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Detection and quantification of structurally related impurities (e.g., de-Boc, decarboxylated, dimerized species) under stressed conditions (acid/base/oxidative/thermal). |
Technical Specifications of (R)-N-Boc-3-pyrrolidineacetic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS); >=99% ee |
| Optical Rotation | -32.0 to -29.0 deg (c=1, in CHCl3) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78.0 to 82.0 °C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-N-Boc-3-pyrrolidineacetic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-N-Boc-3-pyrrolidineacetic acid
Safety Information of (R)-N-Boc-3-pyrrolidineacetic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-N-Boc-3-pyrrolidineacetic acid
Industrial (R)-N-Boc-3-pyrrolidineacetic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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