(S)-1-N-Boc-3-pyrrolidineacetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 204688-61-9 |
| Product name | (S)-1-N-Boc-3-pyrrolidineacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-1-N-Boc-3-pyrrolidineacetic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-1-N-Boc-3-pyrrolidineacetic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-1-N-Boc-3-pyrrolidineacetic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Synthesis of pharmaceutical intermediates for preparation of biologically active compounds | Used as a chiral synthetic intermediate, incorporated into target molecules via coupling reactions, alkylation reactions, and similar processes |
| Organic Synthesis | Precursor for synthesis of chiral compounds | Deprotected (e.g., via acidolysis) to generate free 3-pyrrolidinylacetic acid for subsequent peptide synthesis or structural modification |
| Biopharmaceuticals | Preparation of drug molecules with defined stereochemistry | Stereochemical centers constructed via asymmetric synthesis or chiral resolution processes |
Manufacturing Quality Control of (S)-1-N-Boc-3-pyrrolidineacetic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation on a chiral stationary phase followed by UV detection to determine (S)-enantiomer excess relative to racemate. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine generation to measure trace water based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion and dilution, using mass spectrometry detection. |
| Residual Boc Reagent | HPLC-UV | Specific chromatographic separation and UV quantification of di-tert-butyl dicarbonate and its hydrolysis products. |
| Acid Value | Acid-Base Titration | Neutralization of free carboxylic acid groups with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Optical Rotation | [alpha]D Measurement | Polarimetric measurement at 589 nm (Na D-line) to confirm chiral integrity and specific rotation consistent with (S)-configuration. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to determine D10, D50, D90 values per USP <429>. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., N-Boc-degraded products, diastereomers) using gradient HPLC. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after controlled high-temperature ashing to assess inorganic ash content per USP <281>. |
Technical Specifications of (S)-1-N-Boc-3-pyrrolidineacetic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Optical Rotation | +14.0 to +16.0° (c=1, in methanol) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-1-N-Boc-3-pyrrolidineacetic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-1-N-Boc-3-pyrrolidineacetic acid
Safety Information of (S)-1-N-Boc-3-pyrrolidineacetic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-1-N-Boc-3-pyrrolidineacetic acid
Industrial (S)-1-N-Boc-3-pyrrolidineacetic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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