2-Amino-5-iodopyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 20511-12-0 |
| Product name | 2-Amino-5-iodopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeElectronic GradeMaterial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Amino-5-iodopyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Amino-5-iodopyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Amino-5-iodopyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of anticancer agents (e.g., BTK inhibitors) | Constructs pyridine ring substitution patterns via palladium-catalyzed cross-coupling reactions, such as Suzuki and Heck couplings |
| Pesticide Development | Structural modification unit for novel insecticides and fungicides | Undergoes directed halogenation of heterocyclic compounds to enhance biological activity and selectivity |
| Organic Optoelectronic Materials | Precursor for electron-transport layer materials in organic light-emitting diodes (OLEDs) | Converted into iodopyridyl boronate monomers—used as emissive materials—via metalation (e.g., lithiation followed by reaction with borate esters) |
| Chemical Reagents | Functionalized building block for high-purity analytical standards and custom synthesis services | Purified by recrystallization and column chromatography, then employed in multistep sequential syntheses to support GMP-compliant intermediate manufacturing |
Manufacturing Quality Control of 2-Amino-5-iodopyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase chromatography with UV detection at ~254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separates and detects structurally related impurities (e.g., unreacted 2-aminopyridine, mono/di-iodinated by-products) via retention time and spectral matching. |
| Residual Solvents | GC-FID | Quantifies volatile organic solvents (e.g., DMF, acetonitrile, toluene) using capillary column separation and flame ionization detection against internal standards. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (Pb, Cd, Hg, As, Ni) after acid digestion by detecting elemental mass-to-charge ratios with high sensitivity and multi-element capability. |
| Water Content | Karl Fischer Titration (Coulometric) | Determines trace water via electrochemical generation of iodine and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled ashing at 700–800 °C, expressed as percentage of sample weight. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via comparison to reference material (literature mp: 136–138 °C). |
| Appearance and Color | Visual Inspection & APHA Color Scale | Assesses physical state (crystalline powder), color (white to off-white), and absence of visible particulates or discoloration against standardized color scale. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Quantifies chloride ions using suppressed conductivity detection (IC) or argentometric titration with silver nitrate endpoint detection. |
| Iodine Content | ICP-OES | Measures total iodine concentration after microwave-assisted acid digestion by monitoring characteristic atomic emission lines (e.g., 178.279 nm). |
Technical Specifications of 2-Amino-5-iodopyridine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Amino-5-iodopyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Amino-5-iodopyridine
Packaging of 2-Amino-5-iodopyridine
Industrial 2-Amino-5-iodopyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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