FMOC-L-2-Fluorophe Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 205526-26-7 |
| Product name | FMOC-L-2-Fluorophe |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-L-2-Fluorophe
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-L-2-Fluorophe Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-L-2-Fluorophe
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of anticancer drug candidates | Used as a chiral building block in solid-phase peptide synthesis (SPPS) to incorporate fluorinated phenylalanine residues and enhance metabolic stability |
| Biotechnology | Studying protein structure–function relationships | Applied in site-specific non-canonical amino acid incorporation via genetic code expansion to investigate protein folding and interactions |
| Medical Research | Development of positron emission tomography (PET) tracers | Employed as a precursor for radiolabeling with fluorine-18 to construct tumor-targeted imaging probes |
| Drug Discovery | Improving the bioavailability of peptide-based therapeutics | Used to introduce fluorine atoms into peptide chains to enhance lipophilicity and enzymatic resistance, thereby optimizing pharmacokinetic properties |
Manufacturing Quality Control of FMOC-L-2-Fluorophe
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 265 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., diastereomers, deprotected species, synthesis intermediates) via gradient HPLC with UV detection. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Separates enantiomers on a chiral stationary phase; ee calculated from peak area ratio of FMOC-L-2-fluorophenylalanine vs. FMOC-D-isomer. |
| Residual Solvents | GC-FID | Quantifies residual solvents (e.g., DMF, DCM, methanol) using gas chromatography with flame ionization detection against calibration standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine-based reagent, based on the stoichiometric reaction of water with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Measures trace metals (Pb, Cd, Hg, As, Ni, etc.) after acid digestion using inductively coupled plasma mass spectrometry for ultra-trace sensitivity. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| pH (1% w/v aqueous solution) | pH Meter | Measures hydrogen ion activity in a standardized aqueous suspension using calibrated pH electrode. |
| Specific Optical Rotation | [alpha]D | Determines chiral purity and identity via polarimetric measurement of rotation angle of plane-polarized light at 589 nm. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular variation in laser light scattering intensity. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) using selective agar media and incubation. |
| Heavy Metal (Colorimetric Screening) | Sulfide Precipitation | Semi-quantitative screening for total heavy metals (as Pb) by visual comparison of sulfide precipitate color intensity against lead standard solutions. |
Technical Specifications of FMOC-L-2-Fluorophe
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C to 132°C |
| Optical Rotation | -20.0° to -24.0° (c=1, in DMF) |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-L-2-Fluorophe
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-L-2-Fluorophe
Packaging of FMOC-L-2-Fluorophe
Industrial FMOC-L-2-Fluorophe Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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