China Factory Direct
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| CAS number | 205526-34-7 |
| Product name | Fmoc-D-4-Cyanophenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate for synthesizing peptide-based drugs | Introduces the 4-cyano-D-phenylalanine residue into solid-phase or solution-phase peptide synthesis using the Fmoc protecting group strategy |
| Biopharmaceuticals | Preparation of peptide compounds with specific biological activity | Chemical synthesis incorporating coupling reactions of Fmoc-amino acids |
| Organic Synthesis | Functional group construction in organic molecules | Used as a specialized amino acid bearing a cyanide-containing side chain to build complex organic structures |
| Academic Research | Investigation of structure–function relationships in peptides | Prepared and applied in laboratory studies using standard peptide synthesis protocols |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 268 nm. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase with UV detection; enantiomeric excess calculated from peak areas. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, DCM, MeOH) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol buffer system. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and dilution. |
| Residual Palladium | ICP-MS | Specific quantification of Pd residues from catalytic synthesis steps using isotope-dilution or external calibration. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Fmoc-D-Phe, des-Fmoc derivative, diastereomers) by gradient RP-HPLC. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity against established reference standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid-to-liquid phase transition occurs, using calibrated digital apparatus. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 589 nm to confirm chiral integrity and concentration. |
| Loss on Drying | Gravimetric Thermobalance | Mass loss measured after heating under controlled temperature and vacuum or nitrogen purge to determine volatile content. |
| Residual Chloride | Ion Chromatography | Quantification of chloride ions via suppressed conductivity detection after anion exchange separation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C to 132°C |
| Optical Rotation | -28.0° to -32.0° (c=1, in DMF) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.