D-(-)-Asparagine monohydrate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2058-58-4 |
| Product name | D-(-)-Asparagine monohydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-(-)-Asparagine monohydrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-(-)-Asparagine monohydrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-(-)-Asparagine monohydrate
| Industry | Applications | Process |
|---|---|---|
| Food Industry | Flavor enhancer, nutritional fortifier | Used as an amino acid additive in functional foods, sports drinks, and infant formula; synthesized via fermentation or enzymatic processes and purified prior to incorporation |
| Pharmaceutical Industry | Drug intermediate, component of cell culture media | Applied in the synthesis of anticancer drugs (e.g., asparaginase-based therapeutics) and as an essential amino acid in cell culture media to support cell proliferation and protein synthesis |
| Biotechnology | Component of microbial culture media | Employed as a nitrogen source in microbial fermentation and cell culture processes for the production of antibiotics, enzymes, and other bioproducts |
| Research | Biochemical reagent, tool for metabolic studies | Used as a reference standard or substrate in enzymatic assays, amino acid metabolic pathway studies, and structural and functional analysis of proteins |
Manufacturing Quality Control of D-(-)-Asparagine monohydrate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Asparagine Content) | Acid-Base Titration with HClO4 in non-aqueous medium | Quantifies primary amine group via potentiometric titration using perchloric acid in glacial acetic acid. |
| Optical Rotation | [alpha]D Measurement using Polarimeter | Measures specific rotation at 20 C and 589 nm to confirm chiral purity and identity of D-enantiomer. |
| Loss on Drying | Gravimetric Analysis after drying at 105 C | Determines volatile content by mass loss after standardized oven drying. |
| Residue on Ignition | Gravimetric Ash Test | Measures inorganic impurities as sulfate ash after high-temperature combustion. |
| Chloride Impurity | Potentiometric Titration with AgNO3 | Quantifies chloride ions via argentometric titration using silver nitrate and a silver electrode. |
| Sulfate Impurity | Barium Sulfate Gravimetric Method | Precipitates sulfate as BaSO4 and determines mass after filtration and drying. |
| Heavy Metals (as Pb) | Colorimetric Method with Thioglycolic Acid | Forms colored metal-thioglycolate complexes under alkaline conditions for semi-quantitative comparison. |
| Iron Impurity | UV-Vis Spectrophotometry after 1,10-Phenanthroline complexation | Measures Fe2+ complex absorbance at ~510 nm following reduction and chelation. |
| Related Substances | HPLC with UV detection | Separates and quantifies structurally similar impurities (e.g., L-asparagine, aspartic acid, ammonium salts) using reversed-phase chromatography. |
| Water Content | Karl Fischer Coulometric Titration | Determines trace water via electrochemical iodine generation and stoichiometric reaction with water. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a 1% w/v aqueous solution using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration followed by TSA/TSA-SC Agar Culture | Quantifies aerobic mesophilic microorganisms and detects absence of specified pathogens per pharmacopeial methods. |
Technical Specifications of D-(-)-Asparagine monohydrate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 234-236 °C |
| Optical Rotation | -35.0 to -33.0 deg (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-(-)-Asparagine monohydrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-(-)-Asparagine monohydrate
Packaging of D-(-)-Asparagine monohydrate
Industrial D-(-)-Asparagine monohydrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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