N-METHYLISATIN Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2058-74-4 |
| Product name | N-METHYLISATIN |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-METHYLISATIN
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-METHYLISATIN Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-METHYLISATIN
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate for constructing active molecules containing the indolinone scaffold | Used as a key intermediate in multistep syntheses, e.g., condensation with hydrazides to prepare hydrazone derivatives, or functionalized via reduction and alkylation for kinase inhibitor structural optimization |
| Materials Science | Precursor for organic optoelectronic functional materials | Used to synthesize isatin derivatives with extended π-conjugated structures; conjugated side chains are introduced via Suzuki coupling or Pd-catalyzed C–H activation to produce organic semiconductors or fluorescent dyes |
| Agrochemical R&D | Structural motif for novel insecticidal/fungicidal agents | Employed as a heterocyclic core in structure–activity relationship studies; bioactive groups are introduced via N-methylation and C3 functionalization for lead compound screening |
Manufacturing Quality Control of N-METHYLISATIN
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on calibrated external standards. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine/methanol-based reagent to determine water content by stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for ultra-trace detection. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride anions in aqueous extract using suppressed ion chromatography with standard calibration. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by sulfuric acid treatment and final weighing of non-volatile residue. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, using calibrated capillary method per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, used to assess chiral purity and identity. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measurement upon heating under controlled conditions (e.g., 105 C, 2 h) to determine volatile matter content. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity pattern to calculate volume-based particle size distribution in dry or dispersed state. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode and buffer standards. |
Technical Specifications of N-METHYLISATIN
| Test Item | Specification |
|---|---|
| Appearance | Red solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 198–202°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-METHYLISATIN
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-METHYLISATIN
Packaging of N-METHYLISATIN
Industrial N-METHYLISATIN Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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