(2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 207557-35-5 |
| Product name | (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for protease inhibitor drug synthesis | Produced via N-acylation of (2S)-2-cyanopyrrolidine with chloroacetyl chloride under basic conditions |
Manufacturing Quality Control of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode-array detection; peak purity assessed by spectral comparison. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Chloride Content | Ion Chromatography | Separation of chloride ions on an anion-exchange column followed by conductivity detection. |
| Heavy Metals | ICP-MS | Quantification of trace metals (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm stereochemical integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid-to-liquid phase change occurs. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile inorganic residue remaining after high-temperature ashing at 700-800 C. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to derive volume-based particle size distribution. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity using a calibrated glass electrode system in a saturated aqueous suspension. |
| Organic Volatile Impurities (OVI) | GC-MS | Identification and quantification of structurally undefined volatile impurities using gas chromatography coupled with mass spectrometry. |
Technical Specifications of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (GC-MS) |
| Optical Rotation | -120.0 to -115.0 deg (c=1, in CHCl3) |
| Melting Point | 78.0 to 82.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Safety Information of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
Industrial (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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