1-Benzylpiperidin-4-one hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 20821-52-7 |
| Product name | 1-Benzylpiperidin-4-one hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Benzylpiperidin-4-one hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Benzylpiperidin-4-one hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Benzylpiperidin-4-one hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in the synthesis of antipsychotic drugs, such as risperidone and paliperidone | Acts as a key intermediate in multistep organic synthesis reactions—including reduction, alkylation, or condensation—to prepare target drug molecules |
| Pharmaceuticals | Synthesis of precursors for analgesic drugs and neuroactive compounds | Undergoes functional group transformation at the amino moiety, followed by condensation with carboxylic acids, acid chlorides, or aldehydes/ketones to construct complex molecular frameworks |
| Chemical Research | Used as an organic synthesis building block to construct piperidine-containing compound libraries | Undergoes N-alkylation, Michael addition, or cyclization reactions—under catalytic or non-catalytic conditions—for new drug screening or mechanistic studies |
| Agrochemicals | Synthesis of insecticidal or fungicidal intermediates containing nitrogen-containing heterocyclic structures | Structurally modified to incorporate hydrophobic or target-specific groups, enhancing biological activity and selectivity |
Manufacturing Quality Control of 1-Benzylpiperidin-4-one hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and control based on ICH Q3A/B thresholds. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion; total heavy metals reported as Pb equivalent against USP <231> or Ph. Eur. 2.4.8 limits. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH of Aqueous Solution | pH Meter Measurement | Direct measurement of pH in a 1% w/v aqueous suspension using calibrated pH meter with glass electrode. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, following USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against defined standards. |
| Loss on Drying | Gravimetric Method (Oven Drying) | Weight loss measured after drying at 105 C for 2 hours; reflects volatile matter including residual solvents and moisture. |
| Residue on Ignition | Sulfated Ash Method | Ignition at 600-700 C after sulfuric acid treatment; measures non-volatile inorganic residue per USP <281>. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
Technical Specifications of 1-Benzylpiperidin-4-one hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Benzylpiperidin-4-one hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Benzylpiperidin-4-one hydrochloride
Safety Information of 1-Benzylpiperidin-4-one hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-Benzylpiperidin-4-one hydrochloride
Industrial 1-Benzylpiperidin-4-one hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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