Rp-8-bromo-Cyclic GMPS (sodium salt) Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 208445-06-1 |
| Product name | Rp-8-bromo-Cyclic GMPS (sodium salt) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Rp-8-bromo-Cyclic GMPS (sodium salt)
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Rp-8-bromo-Cyclic GMPS (sodium salt) Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Rp-8-bromo-Cyclic GMPS (sodium salt)
| Industry | Application | Process |
|---|---|---|
| Life Science Research | Specific activator of protein kinase A (PKA) activity for studying cellular signal transduction mechanisms | Added as an aqueous solution in in vitro kinase activity assays or cell culture experiments, typically at concentrations of 1–100 μM for durations ranging from several minutes to several hours |
| Pharmaceutical Development | Pharmacological probe compound used to evaluate the functional role of PKA-dependent pathways in disease models (e.g., cardiac hypertrophy, neurodegenerative disorders) | Administered via intraperitoneal injection or intracerebroventricular delivery in animal models (e.g., mice) to validate target biological effects and support lead compound screening |
| Biochemical Analysis | Positive control and competitive binding assay reagent for the cAMP/PKA signaling pathway | Used as a high-affinity, phosphodiesterase-resistant cAMP analog in radioligand binding assays (e.g., [³H]cAMP competition binding) or fluorescence polarization assays |
Manufacturing Quality Control of Rp-8-bromo-Cyclic GMPS (sodium salt)
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound by UV absorption at specific wavelength using reverse-phase chromatography with calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., acetone, methanol, DMF) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Fe) using inductively coupled plasma mass spectrometry. |
| Sodium Content | Flame Photometry | Measures sodium ion concentration by emission intensity of excited sodium atoms in flame. |
| pH (1% w/v aqueous solution) | Potentiometric Titration | Determines hydrogen ion activity using pH electrode calibrated against standard buffers. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residue. |
| Optical Rotation | [alpha]D Measurement | Determines specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension by analyzing angular variation in laser light scattering. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration. |
| Counterion Identity (Br-) | Ion Chromatography | Confirms bromide anion presence and quantifies it using suppressed conductivity detection. |
| Sterility | Direct Inoculation | Verifies absence of viable microorganisms by incubating product in growth media under controlled conditions. |
| Endotoxins | LAL Assay | Detects bacterial endotoxins using Limulus amebocyte lysate coagulation reaction measured turbidimetrically or chromogenically. |
Technical Specifications of Rp-8-bromo-Cyclic GMPS (sodium salt)
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
| Optical Rotation | -15.0 to -19.0 deg (c=1, H2O) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Rp-8-bromo-Cyclic GMPS (sodium salt)
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of Rp-8-bromo-Cyclic GMPS (sodium salt)
Industrial Rp-8-bromo-Cyclic GMPS (sodium salt) Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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