China Factory Direct
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| CAS number | 20866-48-2 |
| Product name | BOC-TYR(BOC)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Drug synthesis | Used as a protecting group for amino acids to enable selective reaction control during synthesis. |
| Pharmaceuticals | Peptide synthesis | Applied as a tyrosine-protecting derivative to prevent nonspecific reactions during peptide synthesis. |
| Pharmaceuticals | Protein engineering | Employed to protect tyrosine residues during protein synthesis, facilitating subsequent reactions. |
| Chemicals | Organic synthesis | Served as an intermediate in the synthesis of tyrosine-containing compounds, such as antibiotics and hormones. |
| Chemicals | Fine chemical manufacturing | Used as a raw material for producing fine chemicals containing tyrosine structures, including peptides and proteins. |
| Chemicals | Tyrosine group protection in chemical reactions | Applied to prevent tyrosine degradation or undesired side reactions, thereby improving reaction selectivity and yield. |
| Chemicals | Drug intermediate synthesis | Utilized in the synthesis of drug intermediates—such as antibiotics and hormones—to provide the tyrosine scaffold while protecting its hydroxyl and amino groups for downstream transformations. |
| Biotechnology | Peptide and protein synthesis | Applied as a tyrosine-protecting derivative during peptide and protein synthesis to suppress interference from hydroxyl and amino groups. |
| Biotechnology | Biomolecule modification | Used to modify tyrosine residues in biomolecules, enhancing their stability and reaction selectivity. |
| Research | Chemical and biochemical research | Applied to study tyrosine behavior under various reaction conditions and to evaluate the influence of protecting groups on reaction outcomes. |
| Research | Structural studies of peptides and proteins | Used to investigate tyrosine structure and environmental stability within peptides and proteins. |
| Research | Protecting group synthesis research | Applied in the development and evaluation of novel protecting groups for amino acid protection. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., mono-Boc derivatives, deprotected tyrosine) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DCM, MeOH) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine/methanol-based reagent. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation at 589 nm using a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by ignition at 700-800 C followed by precise weighing of residual residue. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular scattering pattern of laser light. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| pH of Aqueous Suspension | pH Meter | Measures pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens (e.g., E. coli) following USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | +13.5 to +15.5° (c=1, in 1M HCl) |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.