2-Thiopheneacetonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 20893-30-5 |
| Product name | 2-Thiopheneacetonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Thiopheneacetonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Thiopheneacetonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Thiopheneacetonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antipsychotic drug quetiapine | Used to construct the quinolinone core via multi-step reactions including cyclization and oxidation with 2-aminothiophene |
| Agrochemicals | Structural building block for novel thiophene-based insecticides and fungicides | Introduced as a heterocyclic side chain, participating in nucleophilic substitution or cross-coupling reactions to modify active molecules |
| Materials Science | Monomeric precursor for conductive polymers and organic semiconductor materials | After hydrolysis of the nitrile group to carboxylic acid, copolymerized with thiophene; or directly employed in Stille and Suzuki couplings to build π-conjugated frameworks |
| Organic Synthesis | Multifunctional synthon for constructing fused thiophene ring systems and nitrogen-containing heterocycles | The nitrile group is convertible to amides, tetrazoles, amines, aldehydes, and other functional groups, enabling broad utility in multi-step total synthesis |
Manufacturing Quality Control of 2-Thiopheneacetonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine is generated in situ to react stoichiometrically with water; endpoint detected by current change. |
| Residue on Ignition | Gravimetric Analysis | Sample is incinerated at 750-800 C, and the non-volatile inorganic residue is weighed after cooling in a desiccator. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of chloride anions on an anion-exchange column followed by conductivity detection and quantification against calibration standards. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Measurement of absorbance of ground-state atoms in a flame or graphite furnace at characteristic wavelength for lead. |
| Sulfate Impurity | Turbidimetric Method | Reaction of sulfate with barium chloride under acidic conditions to form barium sulfate precipitate; turbidity measured spectrophotometrically. |
| Appearance | Visual Inspection | Comparison of sample solution (in specified solvent) against water or reference standard under controlled lighting and against white/black background. |
| Color | Hazen (APHA) Color Scale | Visual or instrumental comparison of sample color intensity to platinum-cobalt standard solutions using a calibrated colorimeter or comparator. |
| Acidity (as H2SO4) | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution with phenolphthalein indicator; endpoint at pH ~8.3. |
| Non-Volatile Residue | Gravimetric Evaporation | Evaporation of a known volume of sample to dryness at 105 C, followed by weighing of residual matter. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation of structurally similar impurities on a reversed-phase column and quantification via UV absorbance at 220 nm or 254 nm. |
| Density | Digital Density Meter | Measurement of oscillating U-tube frequency filled with sample, converted to density using calibration with air and water standards. |
Technical Specifications of 2-Thiopheneacetonitrile
| Test Item | Specification |
|---|---|
| Appearance | Brown liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Thiopheneacetonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Thiopheneacetonitrile
Packaging of 2-Thiopheneacetonitrile
Industrial 2-Thiopheneacetonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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