Ethyl 5-bromonicotinate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 20986-40-7 |
| Product name | Ethyl 5-bromonicotinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl 5-bromonicotinate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl 5-bromonicotinate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl 5-bromonicotinate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antitumor, antiviral, or central nervous system (CNS) drugs | Used to construct heterocyclic or aryl structures via nucleophilic substitution and coupling reactions (e.g., Suzuki, Sonogashira) |
| Agrochemicals | Precursor to active ingredients in novel insecticides or herbicides | Employed in metal-catalyzed coupling or functional group transformation reactions involving the bromine substituent |
| Materials Science | Building block for organic optoelectronic materials (e.g., OLEDs, fluorescent probes) | Directed modification and polymerization leveraging the pyridine ring and bromo substituent |
| Research Reagents | Used in structure–activity relationship (SAR) studies within medicinal chemistry or chemical biology | Serves as a model compound for high-throughput screening or probe design, enabling further functionalization |
Manufacturing Quality Control of Ethyl 5-bromonicotinate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification via retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., ethanol, ethyl acetate) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine-based reagent where water reacts stoichiometrically to determine trace moisture content. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion, measuring emission intensities of metal ions at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection with a carbonate eluent. |
| Acid Value | Acid-Base Titration | Neutralization of free acidic groups with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint detection. |
| Appearance | Visual Inspection | Comparison of sample clarity and color against water-white and colorless standards under controlled white light and specified viewing conditions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700-800 C) to assess inorganic non-volatile impurities. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light through a solution to confirm chiral integrity and absence of racemization. |
| Bulk Density | Tap Density Measurement | Determination of mass per unit volume after standardized tapping per USP <616> to assess flow and handling characteristics. |
Technical Specifications of Ethyl 5-bromonicotinate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl 5-bromonicotinate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl 5-bromonicotinate
Packaging of Ethyl 5-bromonicotinate
Industrial Ethyl 5-bromonicotinate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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