China Factory Direct
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| CAS number | 209917-48-6 |
| Product name | N-tert-Butyl 4-Aminophenylsulfonamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antimicrobial drug intermediate for synthesizing sulfonamide antibiotic derivatives | Used as a key intermediate in structural modification and coupling reactions of sulfonamide drugs, typically introduced into target molecules via diazotization-coupling or amidation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and detection of structurally related impurities (e.g., starting materials, des-tert-butyl analog, oxidation products) using gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., toluene, THF, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying trace water based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, achieving sub-pptr detection limits per ICH Q3D. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of inorganic ash content by ignition at 700–800 °C followed by precise weighing of residual inorganic residue. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, indicating crystallinity and presence of impurities. |
| Appearance & Color | Visual Inspection / Hazen (APHA) Color Scale | Subjective visual assessment of physical state and color intensity compared to platinum-cobalt standards for solution clarity and hue. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| pH of Aqueous Suspension | pH Meter Measurement | Measurement of pH in a defined suspension (e.g., 1% w/v in water) to assess acidic/basic degradation or residual catalysts. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values, critical for filtration and formulation consistency. |
| Bulk & Tapped Density | ASTM D6393 (Tap Density Tester) | Determination of powder flowability and compaction behavior via standardized tapping and volumetric measurement. |
| Microbial Limits | Membrane Filtration + Culture Enumeration | Detection and enumeration of aerobic microorganisms (total viable count), yeast, and mold per Ph. Eur. 2.6.12/USP <61>. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168–172°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.