1,2,4-Trifluoro-5-nitrobenzene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2105-61-5 |
| Product name | 1,2,4-Trifluoro-5-nitrobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeElectronic Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1,2,4-Trifluoro-5-nitrobenzene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1,2,4-Trifluoro-5-nitrobenzene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1,2,4-Trifluoro-5-nitrobenzene
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of insecticidal intermediates | Preparation of fluorinated heterocyclic compounds via nitration, fluorination, and related reactions |
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Construction of fluorinated aromatic structures; participation in multistep synthetic sequences |
| Polymers | Production of fluorinated polymer monomers | Introduction of functional groups via reduction or coupling reactions for specialty resin synthesis |
| Dyes & Pigments | Intermediates for high-performance dye synthesis | Use as fluorinated aromatic nitro compounds in azo dye or fluorescent dye synthesis |
| Electronic Chemicals | Intermediates for liquid crystal materials and semiconductor photoresists | Introduction of specific functional groups via substitution, reduction, and related processes to tailor electrical properties |
Manufacturing Quality Control of 1,2,4-Trifluoro-5-nitrobenzene
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Analyzed using a C18 reversed-phase column, with methanol-water or acetonitrile-water as the mobile phase and UV detection at 254 nm. Quantitation is performed using external or internal standard methods, enabling effective separation and accurate determination of the main component with high precision and good reproducibility. |
| Impurity Profile Analysis | High-Performance Liquid Chromatography (HPLC) | Using the same HPLC conditions as above, trace impurities (e.g., difluoronitrobenzene, monofluoronitrobenzene, unreacted raw materials) are separated by gradient elution. The percentage of impurity peak areas is calculated, following ICH Q3A/B guidelines. |
| Moisture Content | Karl Fischer Titration | The Karl Fischer reagent, composed of iodine, sulfur dioxide, pyridine, and methanol, reacts quantitatively with water. Moisture content is determined by potentiometric or coulometric methods, suitable for precise determination of trace water in organic solvents (accuracy down to 10 ppm). |
| Melting Point | Melting Point Apparatus | A digital melting point apparatus is used to heat the sample gradually. The temperature range from the onset of melting to complete melting is recorded. The theoretical melting point of 2,4,5-trifluoronitrobenzene is approximately 78–80°C, used to assess crystalline purity and the presence of eutectic impurities. |
| Fluorine Content | Oxygen Bomb Combustion - Ion Chromatography (OBC-IC) | The sample is combusted at high temperature in an oxygen bomb, converting fluorine into fluoride ions. After absorption in water, fluoride is quantitatively analyzed by ion chromatography (anion exchange column, eluent: NaHCO₃/Na₂CO₃), ensuring the fluorine atom count matches the molecular formula. |
| Nitro Group Content (Indirect) | UV-Visible Spectrophotometry (UV-Vis) | The characteristic absorption peak of nitrobenzene derivatives is measured at a specific wavelength (e.g., 320–350 nm). The nitro content is estimated using a standard curve method, assisting in verifying structural integrity (should be confirmed with HPLC). |
| Appearance and Color | Visual Inspection + Color Measurement | The sample should appear as white to light yellow crystalline powder, free from visible mechanical impurities. A colorimeter (e.g., APHA or Pt-Co color scale) is used to quantify the yellowness index, ensuring consistent color between batches. |
| Residual Solvents | Gas Chromatography (GC-FID/MS) | Headspace or direct injection is used, with a DB-624 or HP-INNOWAX column and FID or MS detector to determine residual solvents such as acetone, ethanol, and acetonitrile, in compliance with ICH Q3C residual solvent limits. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | The sample is digested with nitric acid and hydrogen peroxide, followed by AAS analysis for heavy metals such as lead, cadmium, mercury, and arsenic, or multi-element detection using ICP-MS, ensuring compliance with pharmaceutical or electronic-grade material standards (e.g., ≤10 ppm). |
Technical Specifications of 1,2,4-Trifluoro-5-nitrobenzene
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 34–36°C |
| Identification (IR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1,2,4-Trifluoro-5-nitrobenzene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1,2,4-Trifluoro-5-nitrobenzene
Safety Information of 1,2,4-Trifluoro-5-nitrobenzene
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 1,2,4-Trifluoro-5-nitrobenzene
Industrial 1,2,4-Trifluoro-5-nitrobenzene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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