China Factory Direct
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| CAS number | 21080-92-2 |
| Product name | 3-Thiophenemalonic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing thienyl-based drugs, used to prepare anti-inflammatory, antitumor, or neuroactive compounds | Constructs the heterocyclic scaffold via Knoevenagel condensation, alkylation, or decarboxylation |
| Pesticides | Used to synthesize herbicidal or insecticidal active ingredients containing a thienyl moiety | Serves as a key building block in heterocycle construction or functional group transformation |
| Materials Science | Monomeric precursor for conductive polymers (e.g., polythiophene derivatives) | Introduces the conjugated system through esterification, coupling, or polymerization reactions |
| Organic Synthesis | General synthon for constructing complex thiophene derivatives | Undergoes C–C bond-forming reactions (e.g., Michael addition, alkylation) at the reactive methylene group |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 220 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally similar impurities using gradient elution and UV absorbance, with identification/quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction with SO2 and base in methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-pptr sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions using anion-exchange column and sodium carbonate/bicarbonate eluent. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate anions using anion-exchange column and suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration (600-750 C) followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using capillary tube method with controlled heating rate; indicative of crystallinity and presence of impurities. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution, used to confirm stereochemical integrity and absence of racemization. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder size distribution by measuring angular variation in laser light scattering intensity across a defined size range. |
| Test Item | Specification |
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| Appearance | White to orange to green crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 145–149 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.3% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.